CYP3A4

ENSG00000160868 - H. sapiens

Pathways

Go term Description
GO:0004497 monooxygenase activity
GO:0005496 steroid binding
GO:0005506 iron ion binding
GO:0008395 steroid hydroxylase activity
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0019899 enzyme binding
GO:0020037 heme binding
GO:0030343 vitamin D3 25-hydroxylase activity
GO:0033780 taurochenodeoxycholate 6alpha-hydroxylase activity
GO:0034875 caffeine oxidase activity
GO:0047638 albendazole monooxygenase activity
GO:0050591 quinine 3-monooxygenase activity
GO:0050649 testosterone 6-beta-hydroxylase activity
GO:0070330 aromatase activity
GO:0070576 vitamin D 24-hydroxylase activity
GO:0101020 estrogen 16-alpha-hydroxylase activity
GO:0102320 1,8-cineole 2-exo-monooxygenase activity

Drugs

Drug name Description
COBICISTAT Cytochrome P450 3A inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
Cyp6a9 D. melanogaster
Cyp6a22 D. melanogaster
Cyp6a21 D. melanogaster
Cyp28d1 D. melanogaster
Cyp28d2 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101266 CSNK2A1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.93673 View
ENSG00000112062 MAPK14 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.931929 View
ENSG00000109320 NFKB1 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.93089 View
ENSG00000122406 RPL5 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.92678 View
ENSG00000112062 MAPK14 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.926031 View
ENSG00000112592 TBP ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.925084 View
ENSG00000113721 PDGFRB ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.923559 View
ENSG00000004700 RECQL ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.921461 View
ENSG00000145604 SKP2 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.921237 View
ENSG00000112592 TBP ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.919208 View
ENSG00000121022 COPS5 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.91854 View
ENSG00000160868 CYP3A4 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.917531 View
ENSG00000012048 BRCA1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.914778 View
ENSG00000070010 UFD1L ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.910707 View
ENSG00000082701 GSK3B ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.910381 View
ENSG00000101868 POLA1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.910273 View
ENSG00000160868 CYP3A4 ENSG00000170315 UBB H. sapiens SDL Slorth 0.909388 View
ENSG00000160868 CYP3A4 ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.907492 View
ENSG00000110107 PRPF19 ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.903762 View
ENSG00000124762 CDKN1A ENSG00000160868 CYP3A4 H. sapiens SDL Slorth 0.901976 View
ENSG00000136807 CDK9 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.900815 View
ENSG00000132155 RAF1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.895617 View
ENSG00000082701 GSK3B ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.891399 View
ENSG00000062822 POLD1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.891118 View
ENSG00000128908 INO80 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.890676 View
ENSG00000110713 NUP98 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.888864 View
ENSG00000142192 APP ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.885087 View
ENSG00000138069 RAB1A ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.884881 View
ENSG00000149554 CHEK1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.881545 View
ENSG00000138376 BARD1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.880906 View
ENSG00000096717 SIRT1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.87828 View
ENSG00000108443 RPS6KB1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.873518 View
ENSG00000141646 SMAD4 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.871318 View
ENSG00000091831 ESR1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.867097 View
ENSG00000135624 CCT7 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.866673 View
ENSG00000097007 ABL1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.864544 View
ENSG00000146648 EGFR ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.860504 View
ENSG00000123124 WWP1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.860211 View
ENSG00000100644 HIF1A ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.857796 View
ENSG00000133316 WDR74 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.852514 View