SIRT1 - CYP3A4

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
CYP3A4	ENSG00000160868	No diseases in record	COBICISTAT	monooxygenase activity steroid binding iron ion binding steroid hydroxylase activity oxidoreductase activity oxygen binding enzyme binding heme binding vitamin D3 25-hydroxylase activity taurochenodeoxycholate 6alpha-hydroxylase activity caffeine oxidase activity albendazole monooxygenase activity quinine 3-monooxygenase activity testosterone 6-beta-hydroxylase activity aromatase activity vitamin D 24-hydroxylase activity estrogen 16-alpha-hydroxylase activity 1,8-cineole 2-exo-monooxygenase activity	Cyp6a9 (D. melanogaster) Cyp6a22 (D. melanogaster) Cyp6a21 (D. melanogaster) Cyp28d1 (D. melanogaster) Cyp28d2 (D. melanogaster)