EGFR - CYP3A4

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
EGFR ENSG00000146648 glioma
NSCLC
AFATINIB
CETUXIMAB
ERLOTINIB
GEFITINIB
LAPATINIB
PANITUMUMAB
VANDETANIB
glycoprotein binding
chromatin binding
double-stranded DNA binding
MAP kinase kinase kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
epidermal growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
integrin binding
protein binding
calmodulin binding
ATP binding
enzyme binding
protein kinase binding
protein phosphatase binding
ubiquitin protein ligase binding
identical protein binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
epidermal growth factor binding
actin filament binding
cadherin binding involved in cell-cell adhesion
nitric-oxide synthase regulator activity
protein domain specific binding
let-23 (C. elegans)
Egfr (D. melanogaster)
CYP3A4 ENSG00000160868

No diseases in record

COBICISTAT
monooxygenase activity
steroid binding
iron ion binding
steroid hydroxylase activity
oxidoreductase activity
oxygen binding
enzyme binding
heme binding
vitamin D3 25-hydroxylase activity
taurochenodeoxycholate 6alpha-hydroxylase activity
caffeine oxidase activity
albendazole monooxygenase activity
quinine 3-monooxygenase activity
testosterone 6-beta-hydroxylase activity
aromatase activity
vitamin D 24-hydroxylase activity
estrogen 16-alpha-hydroxylase activity
1,8-cineole 2-exo-monooxygenase activity
Cyp6a9 (D. melanogaster)
Cyp6a22 (D. melanogaster)
Cyp6a21 (D. melanogaster)
Cyp28d1 (D. melanogaster)
Cyp28d2 (D. melanogaster)