POLA1 - CYP3A4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLA1	ENSG00000101868	No diseases in record	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE NELARABINE	nucleotide binding nucleoside binding DNA binding chromatin binding DNA-directed DNA polymerase activity protein binding 3'-5' exonuclease activity protein kinase binding metal ion binding protein heterodimerization activity 4 iron, 4 sulfur cluster binding DNA primase activity	POL1 (S. cerevisiae) DNApol-alpha180 (D. melanogaster)
CYP3A4	ENSG00000160868	No diseases in record	COBICISTAT	monooxygenase activity steroid binding iron ion binding steroid hydroxylase activity oxidoreductase activity oxygen binding enzyme binding heme binding vitamin D3 25-hydroxylase activity taurochenodeoxycholate 6alpha-hydroxylase activity caffeine oxidase activity albendazole monooxygenase activity quinine 3-monooxygenase activity testosterone 6-beta-hydroxylase activity aromatase activity vitamin D 24-hydroxylase activity estrogen 16-alpha-hydroxylase activity 1,8-cineole 2-exo-monooxygenase activity	Cyp6a9 (D. melanogaster) Cyp6a22 (D. melanogaster) Cyp6a21 (D. melanogaster) Cyp28d1 (D. melanogaster) Cyp28d2 (D. melanogaster)