RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000170881 RNF139 H. sapiens SSL Slorth 0.858818 View
ENSG00000132155 RAF1 ENSG00000196576 PLXNB2 H. sapiens SSL Slorth 0.858615 View
ENSG00000132155 RAF1 ENSG00000155660 PDIA4 H. sapiens SSL Slorth 0.858602 View
ENSG00000132155 RAF1 ENSG00000149269 PAK1 H. sapiens SSL Slorth 0.858491 View
ENSG00000132155 RAF1 ENSG00000173039 RELA H. sapiens SSL Slorth 0.858438 View
ENSG00000132155 RAF1 ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.858175 View
ENSG00000132155 RAF1 ENSG00000141027 NCOR1 H. sapiens SSL Slorth 0.858137 View
ENSG00000132155 RAF1 ENSG00000136854 STXBP1 H. sapiens SSL Slorth 0.857817 View
ENSG00000127022 CANX ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.857804 View
ENSG00000132155 RAF1 ENSG00000178028 DMAP1 H. sapiens SSL Slorth 0.857675 View
ENSG00000104852 SNRNP70 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.857622 View
ENSG00000132155 RAF1 ENSG00000141582 CBX4 H. sapiens SSL Slorth 0.857131 View
ENSG00000113558 SKP1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.85668 View
ENSG00000132155 RAF1 ENSG00000139726 DENR H. sapiens SSL Slorth 0.856544 View
ENSG00000132155 RAF1 ENSG00000180228 PRKRA H. sapiens SSL Slorth 0.856339 View
ENSG00000132155 RAF1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.856107 View
ENSG00000050820 BCAR1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.855687 View
ENSG00000132155 RAF1 ENSG00000198380 GFPT1 H. sapiens SSL Slorth 0.855475 View
ENSG00000132155 RAF1 ENSG00000187266 EPOR H. sapiens SSL Slorth 0.855209 View
ENSG00000132155 RAF1 ENSG00000163029 SMC6 H. sapiens SSL Slorth 0.854319 View
ENSG00000132155 RAF1 ENSG00000167258 CDK12 H. sapiens SSL Slorth 0.854269 View
ENSG00000132155 RAF1 ENSG00000269858 EGLN2 H. sapiens SSL Slorth 0.85392 View
ENSG00000132155 RAF1 ENSG00000166477 LEO1 H. sapiens SSL Slorth 0.853867 View
ENSG00000132155 RAF1 ENSG00000141580 WDR45B H. sapiens SSL Slorth 0.853573 View
ENSG00000132155 RAF1 ENSG00000142208 AKT1 H. sapiens SSL Slorth 0.853289 View
ENSG00000104738 MCM4 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.851668 View
ENSG00000132155 RAF1 ENSG00000166579 NDEL1 H. sapiens SSL Slorth 0.851655 View
ENSG00000132155 RAF1 ENSG00000185591 SP1 H. sapiens SSL Slorth 0.851381 View
ENSG00000132155 RAF1 ENSG00000135363 LMO2 H. sapiens SSL Slorth 0.85138 View
ENSG00000127586 CHTF18 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.851369 View
ENSG00000132155 RAF1 ENSG00000178691 SUZ12 H. sapiens SSL Slorth 0.851157 View
ENSG00000132155 RAF1 ENSG00000182872 RBM10 H. sapiens SSL Slorth 0.850379 View
ENSG00000132155 RAF1 ENSG00000174996 KLC2 H. sapiens SSL Slorth 0.850367 View
ENSG00000132155 RAF1 ENSG00000134717 BTF3L4 H. sapiens SSL Slorth 0.850358 View
ENSG00000132155 RAF1 ENSG00000138696 BMPR1B H. sapiens SSL Slorth 0.850164 View
ENSG00000132155 RAF1 ENSG00000169375 SIN3A H. sapiens SSL Slorth 0.849799 View
ENSG00000132155 RAF1 ENSG00000172795 DCP2 H. sapiens SSL Slorth 0.849702 View
ENSG00000072110 ACTN1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.849589 View
ENSG00000132155 RAF1 ENSG00000170312 CDK1 H. sapiens SSL Slorth 0.849539 View
ENSG00000132155 RAF1 ENSG00000197114 ZGPAT H. sapiens SSL Slorth 0.849145 View