RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000118046 STK11 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.879572 View
ENSG00000132155 RAF1 ENSG00000134759 ELP2 H. sapiens SSL Slorth 0.879218 View
ENSG00000132155 RAF1 ENSG00000169174 PCSK9 H. sapiens SSL Slorth 0.878971 View
ENSG00000132155 RAF1 ENSG00000160691 SHC1 H. sapiens SSL Slorth 0.878573 View
ENSG00000132155 RAF1 ENSG00000163938 GNL3 H. sapiens SSL Slorth 0.878527 View
ENSG00000132155 RAF1 ENSG00000177606 JUN H. sapiens SSL Slorth 0.878368 View
ENSG00000132155 RAF1 ENSG00000177731 FLII H. sapiens SSL Slorth 0.878353 View
ENSG00000132155 RAF1 ENSG00000169100 SLC25A6 H. sapiens SSL Slorth 0.878099 View
ENSG00000132155 RAF1 ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.878039 View
ENSG00000132155 RAF1 ENSG00000164190 NIPBL H. sapiens SSL Slorth 0.877671 View
ENSG00000132155 RAF1 ENSG00000185532 PRKG1 H. sapiens SSL Slorth 0.877633 View
ENSG00000132155 RAF1 ENSG00000137265 IRF4 H. sapiens SSL Slorth 0.877501 View
ENSG00000132155 RAF1 ENSG00000273841 TAF9 H. sapiens SSL Slorth 0.877492 View
ENSG00000073969 NSF ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.877394 View
ENSG00000132155 RAF1 ENSG00000139567 ACVRL1 H. sapiens SSL Slorth 0.877372 View
ENSG00000103275 UBE2I ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.877237 View
ENSG00000132155 RAF1 ENSG00000143322 ABL2 H. sapiens SSL Slorth 0.877159 View
ENSG00000085840 ORC1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.876783 View
ENSG00000132155 RAF1 ENSG00000204217 BMPR2 H. sapiens SSL Slorth 0.876513 View
ENSG00000132155 RAF1 ENSG00000134480 CCNH H. sapiens SSL Slorth 0.876513 View
ENSG00000132155 RAF1 ENSG00000197323 TRIM33 H. sapiens SSL Slorth 0.876237 View
ENSG00000132155 RAF1 ENSG00000167461 RAB8A H. sapiens SSL Slorth 0.87587 View
ENSG00000132155 RAF1 ENSG00000168610 STAT3 H. sapiens SSL Slorth 0.875834 View
ENSG00000132155 RAF1 ENSG00000175634 RPS6KB2 H. sapiens SSL Slorth 0.87552 View
ENSG00000132155 RAF1 ENSG00000173545 ZNF622 H. sapiens SSL Slorth 0.875374 View
ENSG00000132155 RAF1 ENSG00000175216 CKAP5 H. sapiens SSL Slorth 0.875231 View
ENSG00000132155 RAF1 ENSG00000215041 NEURL4 H. sapiens SSL Slorth 0.874755 View
ENSG00000132155 RAF1 ENSG00000214717 ZBED1 H. sapiens SSL Slorth 0.873936 View
ENSG00000132155 RAF1 ENSG00000171105 INSR H. sapiens SSL Slorth 0.873841 View
ENSG00000132155 RAF1 ENSG00000170348 TMED10 H. sapiens SSL Slorth 0.873719 View
ENSG00000112531 QKI ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.873686 View
ENSG00000123374 CDK2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.873332 View
ENSG00000130985 UBA1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.873183 View
ENSG00000132155 RAF1 ENSG00000175643 RMI2 H. sapiens SSL Slorth 0.873177 View
ENSG00000132155 RAF1 ENSG00000167670 CHAF1A H. sapiens SSL Slorth 0.873015 View
ENSG00000109971 HSPA8 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.873007 View
ENSG00000132155 RAF1 ENSG00000140538 NTRK3 H. sapiens SSL Slorth 0.872671 View
ENSG00000132155 RAF1 ENSG00000164327 RICTOR H. sapiens SSL Slorth 0.872413 View
ENSG00000077782 FGFR1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.87226 View
ENSG00000132155 RAF1 ENSG00000151090 THRB H. sapiens SSL Slorth 0.87177 View