RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000203668 CHML H. sapiens SSL Slorth 0.849081 View
ENSG00000100297 MCM5 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.84904 View
ENSG00000132155 RAF1 ENSG00000136352 NKX2-1 H. sapiens SSL Slorth 0.848834 View
ENSG00000132155 RAF1 ENSG00000135945 REV1 H. sapiens SSL Slorth 0.848542 View
ENSG00000132155 RAF1 ENSG00000140939 NOL3 H. sapiens SSL Slorth 0.848385 View
ENSG00000132155 RAF1 ENSG00000164985 PSIP1 H. sapiens SSL Slorth 0.848182 View
ENSG00000132155 RAF1 ENSG00000185236 RAB11B H. sapiens SSL Slorth 0.848023 View
ENSG00000132155 RAF1 ENSG00000188612 SUMO2 H. sapiens SSL Slorth 0.84798 View
ENSG00000132155 RAF1 ENSG00000170315 UBB H. sapiens SSL Slorth 0.847853 View
ENSG00000132155 RAF1 ENSG00000183520 UTP11 H. sapiens SSL Slorth 0.847633 View
ENSG00000132155 RAF1 ENSG00000166855 CLPX H. sapiens SSL Slorth 0.847168 View
ENSG00000132155 RAF1 ENSG00000145495 MARCH6 H. sapiens SSL Slorth 0.847023 View
ENSG00000132155 RAF1 ENSG00000147050 KDM6A H. sapiens SSL Slorth 0.846932 View
ENSG00000075785 RAB7A ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.846822 View
ENSG00000132155 RAF1 ENSG00000157823 AP3S2 H. sapiens SSL Slorth 0.846452 View
ENSG00000132155 RAF1 ENSG00000185920 PTCH1 H. sapiens SSL Slorth 0.846258 View
ENSG00000132155 RAF1 ENSG00000187323 DCC H. sapiens SSL Slorth 0.845844 View
ENSG00000132155 RAF1 ENSG00000169083 AR H. sapiens SSL Slorth 0.845689 View
ENSG00000132155 RAF1 ENSG00000148688 RPP30 H. sapiens SSL Slorth 0.845508 View
ENSG00000079134 THOC1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.845328 View
ENSG00000132155 RAF1 ENSG00000146872 TLK2 H. sapiens SSL Slorth 0.84514 View
ENSG00000132155 RAF1 ENSG00000177613 CSTF2T H. sapiens SSL Slorth 0.845101 View
ENSG00000132155 RAF1 ENSG00000163541 SUCLG1 H. sapiens SSL Slorth 0.845081 View
ENSG00000132155 RAF1 ENSG00000174243 DDX23 H. sapiens SSL Slorth 0.844754 View
ENSG00000132155 RAF1 ENSG00000169016 E2F6 H. sapiens SSL Slorth 0.844667 View
ENSG00000132155 RAF1 ENSG00000139343 SNRPF H. sapiens SSL Slorth 0.844194 View
ENSG00000132155 RAF1 ENSG00000138802 SEC24B H. sapiens SSL Slorth 0.844193 View
ENSG00000012048 BRCA1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.843801 View
ENSG00000132155 RAF1 ENSG00000165169 DYNLT3 H. sapiens SSL Slorth 0.843375 View
ENSG00000077097 TOP2B ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.843262 View
ENSG00000132155 RAF1 ENSG00000142675 CNKSR1 H. sapiens SSL Slorth 0.843257 View
ENSG00000132155 RAF1 ENSG00000133794 ARNTL H. sapiens SSL Slorth 0.843062 View
ENSG00000132155 RAF1 ENSG00000140416 TPM1 H. sapiens SSL Slorth 0.842974 View
ENSG00000132155 RAF1 ENSG00000164548 TRA2A H. sapiens SSL Slorth 0.84293 View
ENSG00000116473 RAP1A ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.842922 View
ENSG00000132155 RAF1 ENSG00000171456 ASXL1 H. sapiens SSL Slorth 0.842599 View
ENSG00000132155 RAF1 ENSG00000166900 STX3 H. sapiens SSL Slorth 0.842534 View
ENSG00000073584 SMARCE1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.842466 View
ENSG00000132155 RAF1 ENSG00000174437 ATP2A2 H. sapiens SSL Slorth 0.84242 View
ENSG00000132155 RAF1 ENSG00000136271 DDX56 H. sapiens SSL Slorth 0.842105 View