RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000049759 NEDD4L ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.871209 View
ENSG00000132155 RAF1 ENSG00000183495 EP400 H. sapiens SSL Slorth 0.871176 View
ENSG00000132155 RAF1 ENSG00000211455 STK38L H. sapiens SSL Slorth 0.871013 View
ENSG00000132155 RAF1 ENSG00000242173 ARHGDIG H. sapiens SSL Slorth 0.870899 View
ENSG00000132155 RAF1 ENSG00000186432 KPNA4 H. sapiens SSL Slorth 0.870797 View
ENSG00000132155 RAF1 ENSG00000141384 TAF4B H. sapiens SSL Slorth 0.870744 View
ENSG00000122512 PMS2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.870705 View
ENSG00000067606 PRKCZ ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.870594 View
ENSG00000115942 ORC2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.870554 View
ENSG00000132155 RAF1 ENSG00000176105 YES1 H. sapiens SSL Slorth 0.869689 View
ENSG00000132155 RAF1 ENSG00000169251 NMD3 H. sapiens SSL Slorth 0.869547 View
ENSG00000132155 RAF1 ENSG00000196396 PTPN1 H. sapiens SSL Slorth 0.869356 View
ENSG00000106263 EIF3B ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.869003 View
ENSG00000132155 RAF1 ENSG00000198898 CAPZA2 H. sapiens SSL Slorth 0.868767 View
ENSG00000132155 RAF1 ENSG00000148229 POLE3 H. sapiens SSL Slorth 0.868607 View
ENSG00000132155 RAF1 ENSG00000156587 UBE2L6 H. sapiens SSL Slorth 0.868432 View
ENSG00000132155 RAF1 ENSG00000197837 HIST4H4 H. sapiens SSL Slorth 0.868296 View
ENSG00000132155 RAF1 ENSG00000153234 NR4A2 H. sapiens SSL Slorth 0.867793 View
ENSG00000125952 MAX ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.867779 View
ENSG00000132155 RAF1 ENSG00000182541 LIMK2 H. sapiens SSL Slorth 0.867716 View
ENSG00000112592 TBP ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.867687 View
ENSG00000132155 RAF1 ENSG00000166794 PPIB H. sapiens SSL Slorth 0.867443 View
ENSG00000132155 RAF1 ENSG00000140403 DNAJA4 H. sapiens SSL Slorth 0.867388 View
ENSG00000105976 MET ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.867359 View
ENSG00000132155 RAF1 ENSG00000142731 PLK4 H. sapiens SSL Slorth 0.866793 View
ENSG00000132155 RAF1 ENSG00000187098 MITF H. sapiens SSL Slorth 0.866713 View
ENSG00000132155 RAF1 ENSG00000247077 PGAM5 H. sapiens SSL Slorth 0.866638 View
ENSG00000132155 RAF1 ENSG00000136936 XPA H. sapiens SSL Slorth 0.866634 View
ENSG00000132155 RAF1 ENSG00000151239 TWF1 H. sapiens SSL Slorth 0.866539 View
ENSG00000132155 RAF1 ENSG00000164695 CHMP4C H. sapiens SSL Slorth 0.86642 View
ENSG00000100906 NFKBIA ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.866357 View
ENSG00000088832 FKBP1A ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.865693 View
ENSG00000130332 LSM7 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.865689 View
ENSG00000132155 RAF1 ENSG00000149923 PPP4C H. sapiens SSL Slorth 0.865033 View
ENSG00000132155 RAF1 ENSG00000204843 DCTN1 H. sapiens SSL Slorth 0.865027 View
ENSG00000132155 RAF1 ENSG00000132383 RPA1 H. sapiens SSL Slorth 0.864973 View
ENSG00000097007 ABL1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.864834 View
ENSG00000132155 RAF1 ENSG00000141959 PFKL H. sapiens SSL Slorth 0.864652 View
ENSG00000132155 RAF1 ENSG00000147224 PRPS1 H. sapiens SSL Slorth 0.864652 View
ENSG00000132155 RAF1 ENSG00000152556 PFKM H. sapiens SSL Slorth 0.864652 View