RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000111875 ASF1A ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.888273 View
ENSG00000132155 RAF1 ENSG00000136931 NR5A1 H. sapiens SSL Slorth 0.888108 View
ENSG00000071564 TCF3 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.887917 View
ENSG00000132155 RAF1 ENSG00000168959 GRM5 H. sapiens SSL Slorth 0.887759 View
ENSG00000132155 RAF1 ENSG00000172340 SUCLG2 H. sapiens SSL Slorth 0.887506 View
ENSG00000132155 RAF1 ENSG00000137955 RABGGTB H. sapiens SSL Slorth 0.886963 View
ENSG00000132155 RAF1 ENSG00000170473 PYM1 H. sapiens SSL Slorth 0.886899 View
ENSG00000004487 KDM1A ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.88657 View
ENSG00000132155 RAF1 ENSG00000189079 ARID2 H. sapiens SSL Slorth 0.886424 View
ENSG00000119541 VPS4B ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.886052 View
ENSG00000132155 RAF1 ENSG00000138814 PPP3CA H. sapiens SSL Slorth 0.88602 View
ENSG00000132155 RAF1 ENSG00000181929 PRKAG1 H. sapiens SSL Slorth 0.885931 View
ENSG00000132155 RAF1 ENSG00000161270 NPHS1 H. sapiens SSL Slorth 0.885819 View
ENSG00000132155 RAF1 ENSG00000136717 BIN1 H. sapiens SSL Slorth 0.885173 View
ENSG00000132155 RAF1 ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.885041 View
ENSG00000132155 RAF1 ENSG00000132470 ITGB4 H. sapiens SSL Slorth 0.884858 View
ENSG00000101266 CSNK2A1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.884341 View
ENSG00000132155 RAF1 ENSG00000177084 POLE H. sapiens SSL Slorth 0.883974 View
ENSG00000132155 RAF1 ENSG00000133740 E2F5 H. sapiens SSL Slorth 0.883955 View
ENSG00000085511 MAP3K4 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.883892 View
ENSG00000132155 RAF1 ENSG00000174371 EXO1 H. sapiens SSL Slorth 0.883821 View
ENSG00000132155 RAF1 ENSG00000198952 SMG5 H. sapiens SSL Slorth 0.883451 View
ENSG00000117222 RBBP5 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.88291 View
ENSG00000132155 RAF1 ENSG00000157873 TNFRSF14 H. sapiens SSL Slorth 0.882878 View
ENSG00000132155 RAF1 ENSG00000135903 PAX3 H. sapiens SSL Slorth 0.88275 View
ENSG00000132155 RAF1 ENSG00000198554 WDHD1 H. sapiens SSL Slorth 0.882478 View
ENSG00000107404 DVL1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.882319 View
ENSG00000132155 RAF1 ENSG00000134698 AGO4 H. sapiens SSL Slorth 0.88197 View
ENSG00000132155 RAF1 ENSG00000182578 CSF1R H. sapiens SSL Slorth 0.881873 View
ENSG00000132155 RAF1 ENSG00000134323 MYCN H. sapiens SSL Slorth 0.881559 View
ENSG00000132155 RAF1 ENSG00000160551 TAOK1 H. sapiens SSL Slorth 0.881542 View
ENSG00000132155 RAF1 ENSG00000167815 PRDX2 H. sapiens SSL Slorth 0.881406 View
ENSG00000132155 RAF1 ENSG00000221914 PPP2R2A H. sapiens SSL Slorth 0.881328 View
ENSG00000132155 RAF1 ENSG00000149503 INCENP H. sapiens SSL Slorth 0.881039 View
ENSG00000132155 RAF1 ENSG00000160208 RRP1B H. sapiens SSL Slorth 0.88062 View
ENSG00000132155 RAF1 ENSG00000196367 TRRAP H. sapiens SSL Slorth 0.880558 View
ENSG00000132155 RAF1 ENSG00000178896 EXOSC4 H. sapiens SSL Slorth 0.880062 View
ENSG00000132155 RAF1 ENSG00000132612 VPS4A H. sapiens SSL Slorth 0.879939 View
ENSG00000132155 RAF1 ENSG00000175662 TOM1L2 H. sapiens SSL Slorth 0.87988 View
ENSG00000132155 RAF1 ENSG00000147133 TAF1 H. sapiens SSL Slorth 0.879766 View