RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000254505 CHMP4A H. sapiens SSL Slorth 0.89371 View
ENSG00000132155 RAF1 ENSG00000132842 AP3B1 H. sapiens SSL Slorth 0.893626 View
ENSG00000132155 RAF1 ENSG00000196218 RYR1 H. sapiens SSL Slorth 0.893548 View
ENSG00000132155 RAF1 ENSG00000134909 ARHGAP32 H. sapiens SSL Slorth 0.893463 View
ENSG00000132155 RAF1 ENSG00000139842 CUL4A H. sapiens SSL Slorth 0.893438 View
ENSG00000132155 RAF1 ENSG00000175792 RUVBL1 H. sapiens SSL Slorth 0.893177 View
ENSG00000132155 RAF1 ENSG00000198959 TGM2 H. sapiens SSL Slorth 0.892957 View
ENSG00000094880 CDC23 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.892748 View
ENSG00000132155 RAF1 ENSG00000134690 CDCA8 H. sapiens SSL Slorth 0.89272 View
ENSG00000132155 RAF1 ENSG00000175305 CCNE2 H. sapiens SSL Slorth 0.892656 View
ENSG00000132155 RAF1 ENSG00000198467 TPM2 H. sapiens SSL Slorth 0.892546 View
ENSG00000132155 RAF1 ENSG00000221823 PPP3R1 H. sapiens SSL Slorth 0.892496 View
ENSG00000132155 RAF1 ENSG00000175354 PTPN2 H. sapiens SSL Slorth 0.892364 View
ENSG00000132155 RAF1 ENSG00000163041 H3F3A H. sapiens SSL Slorth 0.892246 View
ENSG00000113456 RAD1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.892235 View
ENSG00000132155 RAF1 ENSG00000172602 RND1 H. sapiens SSL Slorth 0.892212 View
ENSG00000128052 KDR ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.892203 View
ENSG00000132155 RAF1 ENSG00000169679 BUB1 H. sapiens SSL Slorth 0.892054 View
ENSG00000132155 RAF1 ENSG00000138175 ARL3 H. sapiens SSL Slorth 0.891956 View
ENSG00000104695 PPP2CB ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.891937 View
ENSG00000132155 RAF1 ENSG00000134574 DDB2 H. sapiens SSL Slorth 0.891887 View
ENSG00000132155 RAF1 ENSG00000156052 GNAQ H. sapiens SSL Slorth 0.891831 View
ENSG00000010810 FYN ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.891701 View
ENSG00000132155 RAF1 ENSG00000174738 NR1D2 H. sapiens SSL Slorth 0.891356 View
ENSG00000080986 NDC80 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.891309 View
ENSG00000130177 CDC16 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.891079 View
ENSG00000132155 RAF1 ENSG00000138032 PPM1B H. sapiens SSL Slorth 0.891051 View
ENSG00000132155 RAF1 ENSG00000175745 NR2F1 H. sapiens SSL Slorth 0.890839 View
ENSG00000132155 RAF1 ENSG00000154582 TCEB1 H. sapiens SSL Slorth 0.89045 View
ENSG00000132155 RAF1 ENSG00000133639 BTG1 H. sapiens SSL Slorth 0.88999 View
ENSG00000060069 CTDP1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.889678 View
ENSG00000051180 RAD51 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.889388 View
ENSG00000132155 RAF1 ENSG00000140992 PDPK1 H. sapiens SSL Slorth 0.889381 View
ENSG00000132155 RAF1 ENSG00000145740 SLC30A5 H. sapiens SSL Slorth 0.88932 View
ENSG00000132155 RAF1 ENSG00000145349 CAMK2D H. sapiens SSL Slorth 0.889299 View
ENSG00000132155 RAF1 ENSG00000156475 PPP2R2B H. sapiens SSL Slorth 0.889249 View
ENSG00000132155 RAF1 ENSG00000164754 RAD21 H. sapiens SSL Slorth 0.889229 View
ENSG00000132155 RAF1 ENSG00000136997 MYC H. sapiens SSL Slorth 0.88921 View
ENSG00000132155 RAF1 ENSG00000213281 NRAS H. sapiens SSL Slorth 0.88892 View
ENSG00000114867 EIF4G1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.888895 View