RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.986076 View
ENSG00000132155 RAF1 ENSG00000156299 TIAM1 H. sapiens SDL Slorth 0.986073 View
ENSG00000132155 RAF1 ENSG00000198947 DMD H. sapiens SDL Slorth 0.986055 View
ENSG00000132155 RAF1 ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.985962 View
ENSG00000132155 RAF1 ENSG00000148516 ZEB1 H. sapiens SDL Slorth 0.985923 View
ENSG00000132155 RAF1 ENSG00000140538 NTRK3 H. sapiens SDL Slorth 0.985878 View
ENSG00000132155 RAF1 ENSG00000139318 DUSP6 H. sapiens SDL Slorth 0.985854 View
ENSG00000132155 RAF1 ENSG00000160271 RALGDS H. sapiens SDL Slorth 0.985841 View
ENSG00000132155 RAF1 ENSG00000169100 SLC25A6 H. sapiens SDL Slorth 0.985716 View
ENSG00000132155 RAF1 ENSG00000175376 EIF1AD H. sapiens SDL Slorth 0.985668 View
ENSG00000132155 RAF1 ENSG00000143556 S100A7 H. sapiens SDL Slorth 0.985462 View
ENSG00000132155 RAF1 ENSG00000157168 NRG1 H. sapiens SDL Slorth 0.985367 View
ENSG00000132155 RAF1 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.985258 View
ENSG00000132155 RAF1 ENSG00000141404 GNAL H. sapiens SDL Slorth 0.985204 View
ENSG00000132155 RAF1 ENSG00000173334 TRIB1 H. sapiens SDL Slorth 0.985199 View
ENSG00000132155 RAF1 ENSG00000183337 BCOR H. sapiens SDL Slorth 0.985127 View
ENSG00000132155 RAF1 ENSG00000198399 ITSN2 H. sapiens SDL Slorth 0.985096 View
ENSG00000132155 RAF1 ENSG00000154001 PPP2R5E H. sapiens SDL Slorth 0.985059 View
ENSG00000132155 RAF1 ENSG00000196218 RYR1 H. sapiens SDL Slorth 0.985055 View
ENSG00000132155 RAF1 ENSG00000147614 ATP6V0D2 H. sapiens SDL Slorth 0.985053 View
ENSG00000132155 RAF1 ENSG00000144668 ITGA9 H. sapiens SDL Slorth 0.985029 View
ENSG00000102996 MMP15 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.984876 View
ENSG00000132155 RAF1 ENSG00000185950 IRS2 H. sapiens SDL Slorth 0.984851 View
ENSG00000067829 IDH3G ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.984803 View
ENSG00000077279 DCX ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.984801 View
ENSG00000100372 SLC25A17 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.98479 View
ENSG00000130703 OSBPL2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.98479 View
ENSG00000086619 ERO1B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.984764 View
ENSG00000132155 RAF1 ENSG00000132906 CASP9 H. sapiens SDL Slorth 0.984758 View
ENSG00000100239 PPP6R2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.984744 View
ENSG00000132155 RAF1 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.984723 View
ENSG00000274176 CNOT3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.984684 View
ENSG00000132155 RAF1 ENSG00000133318 RTN3 H. sapiens SDL Slorth 0.984652 View
ENSG00000132155 RAF1 ENSG00000144118 RALB H. sapiens SDL Slorth 0.984622 View
ENSG00000077935 SMC1B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.984575 View
ENSG00000132155 RAF1 ENSG00000196914 ARHGEF12 H. sapiens SDL Slorth 0.984519 View
ENSG00000110048 OSBP ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.9845 View
ENSG00000132155 RAF1 ENSG00000178573 MAF H. sapiens SDL Slorth 0.984494 View
ENSG00000127329 PTPRB ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.98446 View
ENSG00000099785 MARCH2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.984387 View