PMS2 - RAF1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PMS2	ENSG00000122512	colorectal endometrial ovarian medulloblastoma glioma	No drugs in record	DNA binding endonuclease activity protein binding ATP binding ATPase activity single base insertion or deletion binding single-stranded DNA binding MutSalpha complex binding mismatched DNA binding	PMS1 (S. cerevisiae) Pms2 (D. melanogaster)
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)