RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000142945 KIF2C H. sapiens SSL Slorth 0.794401 View
ENSG00000105401 CDC37 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.793703 View
ENSG00000132155 RAF1 ENSG00000163110 PDLIM5 H. sapiens SSL Slorth 0.793406 View
ENSG00000132155 RAF1 ENSG00000163904 SENP2 H. sapiens SSL Slorth 0.793072 View
ENSG00000132155 RAF1 ENSG00000170043 TRAPPC1 H. sapiens SSL Slorth 0.792781 View
ENSG00000132155 RAF1 ENSG00000204120 GIGYF2 H. sapiens SSL Slorth 0.792203 View
ENSG00000116459 ATP5F1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.792167 View
ENSG00000132155 RAF1 ENSG00000132475 H3F3B H. sapiens SSL Slorth 0.791926 View
ENSG00000132155 RAF1 ENSG00000169744 LDB2 H. sapiens SSL Slorth 0.791466 View
ENSG00000132155 RAF1 ENSG00000143632 ACTA1 H. sapiens SSL Slorth 0.791298 View
ENSG00000132155 RAF1 ENSG00000133818 RRAS2 H. sapiens SSL Slorth 0.791236 View
ENSG00000095951 HIVEP1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.79098 View
ENSG00000132155 RAF1 ENSG00000182774 RPS17 H. sapiens SSL Slorth 0.790113 View
ENSG00000132155 RAF1 ENSG00000198033 TUBA3C H. sapiens SSL Slorth 0.789767 View
ENSG00000104375 STK3 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.789516 View
ENSG00000132155 RAF1 ENSG00000179041 RRS1 H. sapiens SSL Slorth 0.789064 View
ENSG00000128739 SNRPN ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.789059 View
ENSG00000132155 RAF1 ENSG00000158186 MRAS H. sapiens SSL Slorth 0.788856 View
ENSG00000132155 RAF1 ENSG00000176108 CHMP6 H. sapiens SSL Slorth 0.788635 View
ENSG00000132155 RAF1 ENSG00000166803 KIAA0101 H. sapiens SSL Slorth 0.788292 View
ENSG00000101343 CRNKL1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.78792 View
ENSG00000132155 RAF1 ENSG00000137996 RTCA H. sapiens SSL Slorth 0.786451 View
ENSG00000132155 RAF1 ENSG00000182521 TBPL2 H. sapiens SSL Slorth 0.786281 View
ENSG00000132155 RAF1 ENSG00000204086 RPA4 H. sapiens SSL Slorth 0.78619 View
ENSG00000132155 RAF1 ENSG00000134987 WDR36 H. sapiens SSL Slorth 0.786003 View
ENSG00000132155 RAF1 ENSG00000184428 TOP1MT H. sapiens SSL Slorth 0.785875 View
ENSG00000132155 RAF1 ENSG00000174672 BRSK2 H. sapiens SSL Slorth 0.785809 View
ENSG00000132155 RAF1 ENSG00000137054 POLR1E H. sapiens SSL Slorth 0.785689 View
ENSG00000132155 RAF1 ENSG00000177272 KCNA3 H. sapiens SSL Slorth 0.785469 View
ENSG00000132155 RAF1 ENSG00000169188 APEX2 H. sapiens SSL Slorth 0.785374 View
ENSG00000132155 RAF1 ENSG00000168061 SAC3D1 H. sapiens SSL Slorth 0.785237 View
ENSG00000132155 RAF1 ENSG00000176444 CLK2 H. sapiens SSL Slorth 0.785048 View
ENSG00000132155 RAF1 ENSG00000197063 MAFG H. sapiens SSL Slorth 0.785016 View
ENSG00000065427 KARS ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.784995 View
ENSG00000132155 RAF1 ENSG00000163577 EIF5A2 H. sapiens SSL Slorth 0.784653 View
ENSG00000132155 RAF1 ENSG00000143569 UBAP2L H. sapiens SSL Slorth 0.784653 View
ENSG00000132155 RAF1 ENSG00000196083 IL1RAP H. sapiens SSL Slorth 0.784493 View
ENSG00000132155 RAF1 ENSG00000143882 ATP6V1C2 H. sapiens SSL Slorth 0.784279 View
ENSG00000116478 HDAC1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.783844 View
ENSG00000132155 RAF1 ENSG00000167996 FTH1 H. sapiens SSL Slorth 0.782815 View