RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000187239 FNBP1 H. sapiens SSL Slorth 0.822972 View
ENSG00000132155 RAF1 ENSG00000139180 NDUFA9 H. sapiens SSL Slorth 0.821813 View
ENSG00000090372 STRN4 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.821683 View
ENSG00000099817 POLR2E ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.821369 View
ENSG00000132155 RAF1 ENSG00000141552 ANAPC11 H. sapiens SSL Slorth 0.821364 View
ENSG00000132155 RAF1 ENSG00000223443 USP17L2 H. sapiens SSL Slorth 0.820857 View
ENSG00000132155 RAF1 ENSG00000197769 MAP1LC3C H. sapiens SSL Slorth 0.82078 View
ENSG00000132155 RAF1 ENSG00000137171 KLC4 H. sapiens SSL Slorth 0.82063 View
ENSG00000132155 RAF1 ENSG00000177169 ULK1 H. sapiens SSL Slorth 0.820294 View
ENSG00000132155 RAF1 ENSG00000176102 CSTF3 H. sapiens SSL Slorth 0.820024 View
ENSG00000132155 RAF1 ENSG00000185624 P4HB H. sapiens SSL Slorth 0.81987 View
ENSG00000132155 RAF1 ENSG00000155511 GRIA1 H. sapiens SSL Slorth 0.819646 View
ENSG00000132155 RAF1 ENSG00000134287 ARF3 H. sapiens SSL Slorth 0.818782 View
ENSG00000132155 RAF1 ENSG00000197694 SPTAN1 H. sapiens SSL Slorth 0.818612 View
ENSG00000064995 TAF11 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.818411 View
ENSG00000132155 RAF1 ENSG00000138613 APH1B H. sapiens SSL Slorth 0.818388 View
ENSG00000132155 RAF1 ENSG00000171094 ALK H. sapiens SSL Slorth 0.81751 View
ENSG00000010017 RANBP9 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.817381 View
ENSG00000132155 RAF1 ENSG00000134910 STT3A H. sapiens SSL Slorth 0.817019 View
ENSG00000132155 RAF1 ENSG00000198586 TLK1 H. sapiens SSL Slorth 0.816867 View
ENSG00000132155 RAF1 ENSG00000137692 DCUN1D5 H. sapiens SSL Slorth 0.814953 View
ENSG00000124762 CDKN1A ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.814627 View
ENSG00000132155 RAF1 ENSG00000135424 ITGA7 H. sapiens SSL Slorth 0.814388 View
ENSG00000132155 RAF1 ENSG00000150995 ITPR1 H. sapiens SSL Slorth 0.813071 View
ENSG00000017797 RALBP1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.812764 View
ENSG00000132155 RAF1 ENSG00000186350 RXRA H. sapiens SSL Slorth 0.812611 View
ENSG00000116288 PARK7 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.812325 View
ENSG00000132155 RAF1 ENSG00000155876 RRAGA H. sapiens SSL Slorth 0.811788 View
ENSG00000132155 RAF1 ENSG00000171435 KSR2 H. sapiens SSL Slorth 0.811774 View
ENSG00000132155 RAF1 ENSG00000152484 USP12 H. sapiens SSL Slorth 0.811508 View
ENSG00000132155 RAF1 ENSG00000158092 NCK1 H. sapiens SSL Slorth 0.811453 View
ENSG00000132155 RAF1 ENSG00000138448 ITGAV H. sapiens SSL Slorth 0.811403 View
ENSG00000132155 RAF1 ENSG00000137642 SORL1 H. sapiens SSL Slorth 0.810855 View
ENSG00000132155 RAF1 ENSG00000154174 TOMM70 H. sapiens SSL Slorth 0.808533 View
ENSG00000132155 RAF1 ENSG00000143473 KCNH1 H. sapiens SSL Slorth 0.806872 View
ENSG00000132155 RAF1 ENSG00000157020 SEC13 H. sapiens SSL Slorth 0.806402 View
ENSG00000101460 MAP1LC3A ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.806243 View
ENSG00000132155 RAF1 ENSG00000198176 TFDP1 H. sapiens SSL Slorth 0.805839 View
ENSG00000132155 RAF1 ENSG00000162298 SYVN1 H. sapiens SSL Slorth 0.805811 View
ENSG00000103769 RAB11A ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.805548 View