RAF1 - CDK12

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
CDK12	ENSG00000167258	serous ovarian	No drugs in record	protein kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity cyclin binding transcription factor binding transcription regulatory region DNA binding	CTK1 (S. cerevisiae) cdk-12 (C. elegans) Cdk12 (D. melanogaster)