RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000110422 HIPK3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.921018 View
ENSG00000007944 MYLIP ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.921013 View
ENSG00000132155 RAF1 ENSG00000135766 EGLN1 H. sapiens SSL Slorth 0.920996 View
ENSG00000132155 RAF1 ENSG00000134215 VAV3 H. sapiens SSL Slorth 0.920954 View
ENSG00000092108 SCFD1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.920887 View
ENSG00000127527 EPS15L1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.920866 View
ENSG00000075413 MARK3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.920813 View
ENSG00000116039 ATP6V1B1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.920802 View
ENSG00000108370 RGS9 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.920799 View
ENSG00000096968 JAK2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.920797 View
ENSG00000132155 RAF1 ENSG00000165525 NEMF H. sapiens SDL Slorth 0.920586 View
ENSG00000132155 RAF1 ENSG00000133316 WDR74 H. sapiens SSL Slorth 0.920566 View
ENSG00000108840 HDAC5 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.920454 View
ENSG00000132155 RAF1 ENSG00000133316 WDR74 H. sapiens SDL Slorth 0.920422 View
ENSG00000129559 NEDD8 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.920362 View
ENSG00000064419 TNPO3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.920324 View
ENSG00000132155 RAF1 ENSG00000138029 HADHB H. sapiens SSL Slorth 0.92032 View
ENSG00000078747 ITCH ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.920251 View
ENSG00000132155 RAF1 ENSG00000143190 POU2F1 H. sapiens SSL Slorth 0.920251 View
ENSG00000132155 RAF1 ENSG00000151247 EIF4E H. sapiens SDL Slorth 0.920235 View
ENSG00000132155 RAF1 ENSG00000171608 PIK3CD H. sapiens SSL Slorth 0.920174 View
ENSG00000078043 PIAS2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.920146 View
ENSG00000132155 RAF1 ENSG00000136826 KLF4 H. sapiens SSL Slorth 0.920017 View
ENSG00000132155 RAF1 ENSG00000182606 TRAK1 H. sapiens SSL Slorth 0.920005 View
ENSG00000132155 RAF1 ENSG00000187017 ESPN H. sapiens SDL Slorth 0.919998 View
ENSG00000132155 RAF1 ENSG00000162613 FUBP1 H. sapiens SSL Slorth 0.919761 View
ENSG00000103197 TSC2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.919757 View
ENSG00000121879 PIK3CA ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.919616 View
ENSG00000132155 RAF1 ENSG00000176986 SEC24C H. sapiens SSL Slorth 0.919607 View
ENSG00000132155 RAF1 ENSG00000135018 UBQLN1 H. sapiens SDL Slorth 0.919603 View
ENSG00000132155 RAF1 ENSG00000185122 HSF1 H. sapiens SSL Slorth 0.919542 View
ENSG00000132155 RAF1 ENSG00000213983 AP1G2 H. sapiens SSL Slorth 0.919414 View
ENSG00000132155 RAF1 ENSG00000179632 MAF1 H. sapiens SDL Slorth 0.919412 View
ENSG00000101412 E2F1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.919401 View
ENSG00000110172 CHORDC1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.919375 View
ENSG00000132155 RAF1 ENSG00000142273 CBLC H. sapiens SSL Slorth 0.919262 View
ENSG00000132155 RAF1 ENSG00000188215 DCUN1D3 H. sapiens SDL Slorth 0.919253 View
ENSG00000132155 RAF1 ENSG00000196866 HIST1H2AD H. sapiens SSL Slorth 0.919205 View
ENSG00000076555 ACACB ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.919187 View
ENSG00000132155 RAF1 ENSG00000167216 KATNAL2 H. sapiens SDL Slorth 0.919137 View