RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000121067 SPOP ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.928864 View
ENSG00000104881 PPP1R13L ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.928859 View
ENSG00000132155 RAF1 ENSG00000213465 ARL2 H. sapiens SSL Slorth 0.928857 View
ENSG00000132155 RAF1 ENSG00000164548 TRA2A H. sapiens SDL Slorth 0.928676 View
ENSG00000132155 RAF1 ENSG00000177302 TOP3A H. sapiens SSL Slorth 0.928615 View
ENSG00000113712 CSNK1A1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.928607 View
ENSG00000132155 RAF1 ENSG00000155363 MOV10 H. sapiens SDL Slorth 0.928412 View
ENSG00000132155 RAF1 ENSG00000198612 COPS8 H. sapiens SSL Slorth 0.928403 View
ENSG00000077782 FGFR1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.928362 View
ENSG00000132155 RAF1 ENSG00000141552 ANAPC11 H. sapiens SDL Slorth 0.928351 View
ENSG00000132155 RAF1 ENSG00000161960 EIF4A1 H. sapiens SDL Slorth 0.92822 View
ENSG00000105173 CCNE1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.928199 View
ENSG00000132155 RAF1 ENSG00000138794 CASP6 H. sapiens SSL Slorth 0.928194 View
ENSG00000132155 RAF1 ENSG00000135766 EGLN1 H. sapiens SDL Slorth 0.928187 View
ENSG00000131759 RARA ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.928127 View
ENSG00000132155 RAF1 ENSG00000166484 MAPK7 H. sapiens SDL Slorth 0.928087 View
ENSG00000132155 RAF1 ENSG00000151067 CACNA1C H. sapiens SSL Slorth 0.928074 View
ENSG00000132155 RAF1 ENSG00000144645 OSBPL10 H. sapiens SDL Slorth 0.928034 View
ENSG00000090060 PAPOLA ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.927991 View
ENSG00000132155 RAF1 ENSG00000221978 CCNL2 H. sapiens SDL Slorth 0.927809 View
ENSG00000132155 RAF1 ENSG00000153922 CHD1 H. sapiens SDL Slorth 0.927765 View
ENSG00000115904 SOS1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.92765 View
ENSG00000132155 RAF1 ENSG00000144134 RABL2A H. sapiens SDL Slorth 0.927632 View
ENSG00000132155 RAF1 ENSG00000147647 DPYS H. sapiens SDL Slorth 0.927574 View
ENSG00000132155 RAF1 ENSG00000144644 GADL1 H. sapiens SDL Slorth 0.927574 View
ENSG00000132155 RAF1 ENSG00000197299 BLM H. sapiens SSL Slorth 0.927543 View
ENSG00000111252 SH2B3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.92753 View
ENSG00000132155 RAF1 ENSG00000132437 DDC H. sapiens SDL Slorth 0.92751 View
ENSG00000013561 RNF14 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.927449 View
ENSG00000132155 RAF1 ENSG00000164056 SPRY1 H. sapiens SSL Slorth 0.927439 View
ENSG00000132155 RAF1 ENSG00000157456 CCNB2 H. sapiens SSL Slorth 0.927413 View
ENSG00000132155 RAF1 ENSG00000220205 VAMP2 H. sapiens SSL Slorth 0.927346 View
ENSG00000067900 ROCK1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.927269 View
ENSG00000075785 RAB7A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.927181 View
ENSG00000132155 RAF1 ENSG00000204209 DAXX H. sapiens SDL Slorth 0.927164 View
ENSG00000110092 CCND1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.927036 View
ENSG00000132155 RAF1 ENSG00000137193 PIM1 H. sapiens SSL Slorth 0.927031 View
ENSG00000132155 RAF1 ENSG00000181788 SIAH2 H. sapiens SSL Slorth 0.927006 View
ENSG00000132155 RAF1 ENSG00000183337 BCOR H. sapiens SSL Slorth 0.92698 View
ENSG00000132155 RAF1 ENSG00000134698 AGO4 H. sapiens SDL Slorth 0.9269 View