RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000261832 RP11-435I10.4 H. sapiens SDL Slorth 0.930548 View
ENSG00000132155 RAF1 ENSG00000159082 SYNJ1 H. sapiens SDL Slorth 0.930487 View
ENSG00000121892 PDS5A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.930468 View
ENSG00000132155 RAF1 ENSG00000166197 NOLC1 H. sapiens SSL Slorth 0.930409 View
ENSG00000132155 RAF1 ENSG00000148908 RGS10 H. sapiens SDL Slorth 0.930332 View
ENSG00000132155 RAF1 ENSG00000143632 ACTA1 H. sapiens SDL Slorth 0.930313 View
ENSG00000132155 RAF1 ENSG00000165527 ARF6 H. sapiens SSL Slorth 0.930309 View
ENSG00000121152 NCAPH ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.93018 View
ENSG00000132155 RAF1 ENSG00000136848 DAB2IP H. sapiens SSL Slorth 0.930134 View
ENSG00000132155 RAF1 ENSG00000136750 GAD2 H. sapiens SDL Slorth 0.930087 View
ENSG00000132155 RAF1 ENSG00000138107 ACTR1A H. sapiens SSL Slorth 0.930065 View
ENSG00000132155 RAF1 ENSG00000171824 EXOSC10 H. sapiens SSL Slorth 0.930065 View
ENSG00000132155 RAF1 ENSG00000140455 USP3 H. sapiens SDL Slorth 0.930054 View
ENSG00000132155 RAF1 ENSG00000134602 STK26 H. sapiens SDL Slorth 0.929909 View
ENSG00000132155 RAF1 ENSG00000153140 CETN3 H. sapiens SDL Slorth 0.929819 View
ENSG00000132155 RAF1 ENSG00000163629 PTPN13 H. sapiens SSL Slorth 0.929779 View
ENSG00000102978 POLR2C ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.929772 View
ENSG00000132155 RAF1 ENSG00000142273 CBLC H. sapiens SDL Slorth 0.929764 View
ENSG00000101911 PRPS2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.929739 View
ENSG00000132155 RAF1 ENSG00000140553 UNC45A H. sapiens SSL Slorth 0.929733 View
ENSG00000126214 KLC1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.929659 View
ENSG00000123374 CDK2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.92964 View
ENSG00000105974 CAV1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.929607 View
ENSG00000132155 RAF1 ENSG00000160271 RALGDS H. sapiens SSL Slorth 0.929597 View
ENSG00000132155 RAF1 ENSG00000136931 NR5A1 H. sapiens SDL Slorth 0.929484 View
ENSG00000070756 PABPC1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.929477 View
ENSG00000132155 RAF1 ENSG00000136631 VPS45 H. sapiens SSL Slorth 0.929442 View
ENSG00000132155 RAF1 ENSG00000133835 HSD17B4 H. sapiens SDL Slorth 0.929426 View
ENSG00000132155 RAF1 ENSG00000163029 SMC6 H. sapiens SDL Slorth 0.929394 View
ENSG00000132155 RAF1 ENSG00000134853 PDGFRA H. sapiens SSL Slorth 0.929376 View
ENSG00000073111 MCM2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.929313 View
ENSG00000132155 RAF1 ENSG00000178997 EXD1 H. sapiens SDL Slorth 0.929302 View
ENSG00000132155 RAF1 ENSG00000138190 EXOC6 H. sapiens SSL Slorth 0.929245 View
ENSG00000132155 RAF1 ENSG00000187735 TCEA1 H. sapiens SSL Slorth 0.929208 View
ENSG00000108953 YWHAE ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.929196 View
ENSG00000101460 MAP1LC3A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.929096 View
ENSG00000132155 RAF1 ENSG00000187840 EIF4EBP1 H. sapiens SSL Slorth 0.928966 View
ENSG00000132155 RAF1 ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.928951 View
ENSG00000132155 RAF1 ENSG00000181090 EHMT1 H. sapiens SSL Slorth 0.928949 View
ENSG00000109971 HSPA8 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.928937 View