RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000104375 STK3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.926825 View
ENSG00000132155 RAF1 ENSG00000149182 ARFGAP2 H. sapiens SDL Slorth 0.926824 View
ENSG00000132155 RAF1 ENSG00000163041 H3F3A H. sapiens SDL Slorth 0.926648 View
ENSG00000132155 RAF1 ENSG00000168818 STX18 H. sapiens SDL Slorth 0.926625 View
ENSG00000132155 RAF1 ENSG00000133216 EPHB2 H. sapiens SSL Slorth 0.926579 View
ENSG00000132155 RAF1 ENSG00000155959 VBP1 H. sapiens SSL Slorth 0.926576 View
ENSG00000072803 FBXW11 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.92657 View
ENSG00000132155 RAF1 ENSG00000177879 AP3S1 H. sapiens SSL Slorth 0.926519 View
ENSG00000132155 RAF1 ENSG00000137822 TUBGCP4 H. sapiens SSL Slorth 0.926497 View
ENSG00000091009 RBM27 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.926451 View
ENSG00000123143 PKN1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.926446 View
ENSG00000132155 RAF1 ENSG00000136381 IREB2 H. sapiens SSL Slorth 0.926247 View
ENSG00000132155 RAF1 ENSG00000135100 HNF1A H. sapiens SDL Slorth 0.92623 View
ENSG00000130939 UBE4B ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.926159 View
ENSG00000132155 RAF1 ENSG00000177283 FZD8 H. sapiens SDL Slorth 0.92612 View
ENSG00000077522 ACTN2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.926038 View
ENSG00000103194 USP10 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.925994 View
ENSG00000070950 RAD18 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.925964 View
ENSG00000132155 RAF1 ENSG00000196459 TRAPPC2 H. sapiens SSL Slorth 0.925943 View
ENSG00000071575 TRIB2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.925921 View
ENSG00000132155 RAF1 ENSG00000182287 AP1S2 H. sapiens SSL Slorth 0.92592 View
ENSG00000132155 RAF1 ENSG00000133706 LARS H. sapiens SSL Slorth 0.925812 View
ENSG00000132155 RAF1 ENSG00000137497 NUMA1 H. sapiens SSL Slorth 0.925764 View
ENSG00000132155 RAF1 ENSG00000205726 ITSN1 H. sapiens SSL Slorth 0.925749 View
ENSG00000095015 MAP3K1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.925734 View
ENSG00000132155 RAF1 ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.925728 View
ENSG00000132155 RAF1 ENSG00000174405 LIG4 H. sapiens SSL Slorth 0.925716 View
ENSG00000104964 AES ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.925679 View
ENSG00000132155 RAF1 ENSG00000163602 RYBP H. sapiens SSL Slorth 0.925622 View
ENSG00000006451 RALA ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.925547 View
ENSG00000132155 RAF1 ENSG00000133101 CCNA1 H. sapiens SDL Slorth 0.925523 View
ENSG00000109819 PPARGC1A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.925511 View
ENSG00000132155 RAF1 ENSG00000148737 TCF7L2 H. sapiens SDL Slorth 0.925431 View
ENSG00000132155 RAF1 ENSG00000159461 AMFR H. sapiens SSL Slorth 0.925413 View
ENSG00000132155 RAF1 ENSG00000175792 RUVBL1 H. sapiens SDL Slorth 0.925337 View
ENSG00000132155 RAF1 ENSG00000136754 ABI1 H. sapiens SSL Slorth 0.925317 View
ENSG00000132155 RAF1 ENSG00000148943 LIN7C H. sapiens SSL Slorth 0.9252 View
ENSG00000072110 ACTN1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.925105 View
ENSG00000132155 RAF1 ENSG00000143878 RHOB H. sapiens SSL Slorth 0.924995 View
ENSG00000132155 RAF1 ENSG00000173674 EIF1AX H. sapiens SSL Slorth 0.924789 View