RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000140262 TCF12 H. sapiens SSL Slorth 0.93419 View
ENSG00000132155 RAF1 ENSG00000198807 PAX9 H. sapiens SDL Slorth 0.934123 View
ENSG00000092531 SNAP23 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.934081 View
ENSG00000132155 RAF1 ENSG00000163939 PBRM1 H. sapiens SDL Slorth 0.934036 View
ENSG00000132155 RAF1 ENSG00000136238 RAC1 H. sapiens SDL Slorth 0.933971 View
ENSG00000132155 RAF1 ENSG00000184787 UBE2G2 H. sapiens SDL Slorth 0.93386 View
ENSG00000131507 NDFIP1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.933696 View
ENSG00000132155 RAF1 ENSG00000204120 GIGYF2 H. sapiens SDL Slorth 0.933676 View
ENSG00000132155 RAF1 ENSG00000154380 ENAH H. sapiens SSL Slorth 0.933674 View
ENSG00000132155 RAF1 ENSG00000132356 PRKAA1 H. sapiens SSL Slorth 0.933606 View
ENSG00000050820 BCAR1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.933432 View
ENSG00000119866 BCL11A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.933357 View
ENSG00000132155 RAF1 ENSG00000171960 PPIH H. sapiens SSL Slorth 0.933294 View
ENSG00000025800 KPNA6 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.93329 View
ENSG00000132155 RAF1 ENSG00000135604 STX11 H. sapiens SDL Slorth 0.933288 View
ENSG00000124788 ATXN1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.933252 View
ENSG00000108179 PPIF ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.933233 View
ENSG00000132155 RAF1 ENSG00000134954 ETS1 H. sapiens SDL Slorth 0.933176 View
ENSG00000125971 DYNLRB1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.933138 View
ENSG00000132155 RAF1 ENSG00000183474 GTF2H2C H. sapiens SDL Slorth 0.933134 View
ENSG00000132155 RAF1 ENSG00000182179 UBA7 H. sapiens SDL Slorth 0.933128 View
ENSG00000132155 RAF1 ENSG00000159216 RUNX1 H. sapiens SDL Slorth 0.933044 View
ENSG00000132155 RAF1 ENSG00000184481 FOXO4 H. sapiens SSL Slorth 0.933031 View
ENSG00000132155 RAF1 ENSG00000153944 MSI2 H. sapiens SDL Slorth 0.933004 View
ENSG00000132155 RAF1 ENSG00000145555 MYO10 H. sapiens SSL Slorth 0.932978 View
ENSG00000132155 RAF1 ENSG00000145907 G3BP1 H. sapiens SSL Slorth 0.932962 View
ENSG00000131023 LATS1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.932927 View
ENSG00000132155 RAF1 ENSG00000162909 CAPN2 H. sapiens SSL Slorth 0.932835 View
ENSG00000132155 RAF1 ENSG00000136279 DBNL H. sapiens SSL Slorth 0.932609 View
ENSG00000120833 SOCS2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.932526 View
ENSG00000132155 RAF1 ENSG00000138346 DNA2 H. sapiens SSL Slorth 0.932526 View
ENSG00000132155 RAF1 ENSG00000168918 INPP5D H. sapiens SSL Slorth 0.932525 View
ENSG00000044115 CTNNA1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.932417 View
ENSG00000130779 CLIP1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.932344 View
ENSG00000132155 RAF1 ENSG00000136574 GATA4 H. sapiens SDL Slorth 0.932321 View
ENSG00000132155 RAF1 ENSG00000141543 EIF4A3 H. sapiens SDL Slorth 0.932257 View
ENSG00000100092 SH3BP1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.932246 View
ENSG00000132155 RAF1 ENSG00000186716 BCR H. sapiens SSL Slorth 0.932225 View
ENSG00000131381 RBSN ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.932209 View
ENSG00000132155 RAF1 ENSG00000140990 NDUFB10 H. sapiens SDL Slorth 0.932151 View