RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000172348 RCAN2 H. sapiens SDL Slorth 0.917534 View
ENSG00000124222 STX16 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.91748 View
ENSG00000132155 RAF1 ENSG00000161800 RACGAP1 H. sapiens SSL Slorth 0.917472 View
ENSG00000132155 RAF1 ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.917409 View
ENSG00000132155 RAF1 ENSG00000167548 KMT2D H. sapiens SDL Slorth 0.917291 View
ENSG00000132155 RAF1 ENSG00000166797 FAM96A H. sapiens SDL Slorth 0.917274 View
ENSG00000132155 RAF1 ENSG00000132694 ARHGEF11 H. sapiens SSL Slorth 0.917123 View
ENSG00000108587 GOSR1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.917103 View
ENSG00000085832 EPS15 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.917072 View
ENSG00000066230 SLC9A3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.917071 View
ENSG00000132155 RAF1 ENSG00000166869 CHP2 H. sapiens SDL Slorth 0.91695 View
ENSG00000132155 RAF1 ENSG00000151502 VPS26B H. sapiens SDL Slorth 0.916835 View
ENSG00000132155 RAF1 ENSG00000136100 VPS36 H. sapiens SSL Slorth 0.916821 View
ENSG00000132155 RAF1 ENSG00000159352 PSMD4 H. sapiens SDL Slorth 0.916819 View
ENSG00000086827 ZW10 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.916798 View
ENSG00000131263 RLIM ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.916797 View
ENSG00000108654 DDX5 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.91678 View
ENSG00000132155 RAF1 ENSG00000184557 SOCS3 H. sapiens SSL Slorth 0.91663 View
ENSG00000122406 RPL5 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.916539 View
ENSG00000105325 FZR1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.916487 View
ENSG00000132155 RAF1 ENSG00000171132 PRKCE H. sapiens SDL Slorth 0.916319 View
ENSG00000132155 RAF1 ENSG00000166233 ARIH1 H. sapiens SDL Slorth 0.916306 View
ENSG00000132155 RAF1 ENSG00000135966 TGFBRAP1 H. sapiens SDL Slorth 0.916295 View
ENSG00000132155 RAF1 ENSG00000141378 PTRH2 H. sapiens SSL Slorth 0.916283 View
ENSG00000132155 RAF1 ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.916275 View
ENSG00000132155 RAF1 ENSG00000179583 CIITA H. sapiens SDL Slorth 0.916143 View
ENSG00000132155 RAF1 ENSG00000178184 PARD6G H. sapiens SSL Slorth 0.916067 View
ENSG00000132155 RAF1 ENSG00000142192 APP H. sapiens SDL Slorth 0.916039 View
ENSG00000130787 HIP1R ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.915977 View
ENSG00000132155 RAF1 ENSG00000183853 KIRREL H. sapiens SSL Slorth 0.915977 View
ENSG00000132155 RAF1 ENSG00000141556 TBCD H. sapiens SSL Slorth 0.91596 View
ENSG00000132155 RAF1 ENSG00000137154 RPS6 H. sapiens SDL Slorth 0.915954 View
ENSG00000124198 ARFGEF2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.915939 View
ENSG00000132155 RAF1 ENSG00000140983 RHOT2 H. sapiens SSL Slorth 0.915936 View
ENSG00000132155 RAF1 ENSG00000182979 MTA1 H. sapiens SSL Slorth 0.91591 View
ENSG00000114867 EIF4G1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.915886 View
ENSG00000101844 ATG4A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.91588 View
ENSG00000132155 RAF1 ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.915748 View
ENSG00000132155 RAF1 ENSG00000141646 SMAD4 H. sapiens SSL Slorth 0.915629 View
ENSG00000132155 RAF1 ENSG00000172409 CLP1 H. sapiens SDL Slorth 0.915578 View