RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000137270 GCM1 H. sapiens SSL Slorth 0.912197 View
ENSG00000132155 RAF1 ENSG00000242247 ARFGAP3 H. sapiens SDL Slorth 0.912125 View
ENSG00000101040 ZMYND8 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.912121 View
ENSG00000103222 ABCC1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.912074 View
ENSG00000132155 RAF1 ENSG00000169189 NSMCE1 H. sapiens SSL Slorth 0.911962 View
ENSG00000101945 SUV39H1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.911941 View
ENSG00000132155 RAF1 ENSG00000168397 ATG4B H. sapiens SSL Slorth 0.911921 View
ENSG00000121879 PIK3CA ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.911879 View
ENSG00000132155 RAF1 ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.911821 View
ENSG00000078674 PCM1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.9118 View
ENSG00000082701 GSK3B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.911787 View
ENSG00000132155 RAF1 ENSG00000154001 PPP2R5E H. sapiens SSL Slorth 0.911738 View
ENSG00000132155 RAF1 ENSG00000149968 MMP3 H. sapiens SDL Slorth 0.911677 View
ENSG00000132155 RAF1 ENSG00000156976 EIF4A2 H. sapiens SSL Slorth 0.911623 View
ENSG00000132155 RAF1 ENSG00000184787 UBE2G2 H. sapiens SSL Slorth 0.91157 View
ENSG00000132155 RAF1 ENSG00000173812 EIF1 H. sapiens SDL Slorth 0.911568 View
ENSG00000132155 RAF1 ENSG00000148660 CAMK2G H. sapiens SSL Slorth 0.911466 View
ENSG00000117399 CDC20 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.911436 View
ENSG00000061273 HDAC7 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.911434 View
ENSG00000132155 RAF1 ENSG00000138663 COPS4 H. sapiens SSL Slorth 0.911357 View
ENSG00000132155 RAF1 ENSG00000164597 COG5 H. sapiens SSL Slorth 0.91135 View
ENSG00000132155 RAF1 ENSG00000161547 SRSF2 H. sapiens SSL Slorth 0.911323 View
ENSG00000088808 PPP1R13B ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.91131 View
ENSG00000132155 RAF1 ENSG00000196235 SUPT5H H. sapiens SSL Slorth 0.911207 View
ENSG00000132155 RAF1 ENSG00000150459 SAP18 H. sapiens SSL Slorth 0.910969 View
ENSG00000132155 RAF1 ENSG00000179776 CDH5 H. sapiens SSL Slorth 0.910826 View
ENSG00000132155 RAF1 ENSG00000198887 SMC5 H. sapiens SSL Slorth 0.910744 View
ENSG00000132155 RAF1 ENSG00000171223 JUNB H. sapiens SSL Slorth 0.910543 View
ENSG00000132155 RAF1 ENSG00000162961 DPY30 H. sapiens SSL Slorth 0.910534 View
ENSG00000132155 RAF1 ENSG00000165732 DDX21 H. sapiens SDL Slorth 0.910512 View
ENSG00000132155 RAF1 ENSG00000172315 TP53RK H. sapiens SSL Slorth 0.910501 View
ENSG00000132155 RAF1 ENSG00000140464 PML H. sapiens SSL Slorth 0.910485 View
ENSG00000125354 SEPT6 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.910453 View
ENSG00000132155 RAF1 ENSG00000164654 MIOS H. sapiens SDL Slorth 0.910445 View
ENSG00000132155 RAF1 ENSG00000196531 NACA H. sapiens SSL Slorth 0.91044 View
ENSG00000132155 RAF1 ENSG00000164045 CDC25A H. sapiens SSL Slorth 0.910423 View
ENSG00000125968 ID1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.910273 View
ENSG00000099956 SMARCB1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.910147 View
ENSG00000132155 RAF1 ENSG00000158987 RAPGEF6 H. sapiens SSL Slorth 0.910138 View
ENSG00000063244 U2AF2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.910013 View