RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000132155 RAF1 ENSG00000173801 JUP H. sapiens SSL Slorth 0.909986 View
ENSG00000132155 RAF1 ENSG00000144488 ESPNL H. sapiens SDL Slorth 0.909974 View
ENSG00000132155 RAF1 ENSG00000154710 RABGEF1 H. sapiens SDL Slorth 0.909933 View
ENSG00000132155 RAF1 ENSG00000161057 PSMC2 H. sapiens SDL Slorth 0.909907 View
ENSG00000118503 TNFAIP3 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.90977 View
ENSG00000132155 RAF1 ENSG00000178921 PFAS H. sapiens SSL Slorth 0.909768 View
ENSG00000132155 RAF1 ENSG00000140332 TLE3 H. sapiens SSL Slorth 0.909763 View
ENSG00000132155 RAF1 ENSG00000182481 KPNA2 H. sapiens SSL Slorth 0.909759 View
ENSG00000017797 RALBP1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.909646 View
ENSG00000080503 SMARCA2 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.90941 View
ENSG00000109320 NFKB1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.909311 View
ENSG00000112039 FANCE ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.909138 View
ENSG00000132155 RAF1 ENSG00000171105 INSR H. sapiens SDL Slorth 0.909101 View
ENSG00000132155 RAF1 ENSG00000177106 EPS8L2 H. sapiens SDL Slorth 0.909086 View
ENSG00000005156 LIG3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.909009 View
ENSG00000132155 RAF1 ENSG00000151461 UPF2 H. sapiens SSL Slorth 0.908945 View
ENSG00000132155 RAF1 ENSG00000204217 BMPR2 H. sapiens SDL Slorth 0.908877 View
ENSG00000132155 RAF1 ENSG00000166266 CUL5 H. sapiens SSL Slorth 0.908843 View
ENSG00000132155 RAF1 ENSG00000160867 FGFR4 H. sapiens SSL Slorth 0.908839 View
ENSG00000101558 VAPA ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.908799 View
ENSG00000120438 TCP1 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.908783 View
ENSG00000132155 RAF1 ENSG00000169398 PTK2 H. sapiens SSL Slorth 0.908739 View
ENSG00000132155 RAF1 ENSG00000175390 EIF3F H. sapiens SSL Slorth 0.908543 View
ENSG00000132155 RAF1 ENSG00000143761 ARF1 H. sapiens SSL Slorth 0.908397 View
ENSG00000110330 BIRC2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.908302 View
ENSG00000132155 RAF1 ENSG00000140455 USP3 H. sapiens SSL Slorth 0.908228 View
ENSG00000132155 RAF1 ENSG00000173327 MAP3K11 H. sapiens SSL Slorth 0.908227 View
ENSG00000132155 RAF1 ENSG00000138385 SSB H. sapiens SSL Slorth 0.908199 View
ENSG00000121057 AKAP1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.908173 View
ENSG00000132155 RAF1 ENSG00000198522 GPN1 H. sapiens SSL Slorth 0.908146 View
ENSG00000115464 USP34 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.908024 View
ENSG00000132155 RAF1 ENSG00000173599 PC H. sapiens SSL Slorth 0.908005 View
ENSG00000132155 RAF1 ENSG00000157227 MMP14 H. sapiens SSL Slorth 0.907988 View
ENSG00000104388 RAB2A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.907918 View
ENSG00000116251 RPL22 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.907888 View
ENSG00000096746 HNRNPH3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.907871 View
ENSG00000132155 RAF1 ENSG00000138095 LRPPRC H. sapiens SSL Slorth 0.90776 View
ENSG00000132155 RAF1 ENSG00000136518 ACTL6A H. sapiens SSL Slorth 0.907757 View
ENSG00000061938 TNK2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.907745 View
ENSG00000000938 FGR ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.907664 View