RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000034152 MAP2K3 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.945082 View
ENSG00000132155 RAF1 ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.945068 View
ENSG00000132155 RAF1 ENSG00000172053 QARS H. sapiens SSL Slorth 0.945049 View
ENSG00000132155 RAF1 ENSG00000181090 EHMT1 H. sapiens SDL Slorth 0.944983 View
ENSG00000113558 SKP1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.944909 View
ENSG00000132155 RAF1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.944859 View
ENSG00000132155 RAF1 ENSG00000143190 POU2F1 H. sapiens SDL Slorth 0.944824 View
ENSG00000132155 RAF1 ENSG00000164190 NIPBL H. sapiens SDL Slorth 0.944706 View
ENSG00000132155 RAF1 ENSG00000215021 PHB2 H. sapiens SSL Slorth 0.944705 View
ENSG00000011485 PPP5C ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.944677 View
ENSG00000130402 ACTN4 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.944649 View
ENSG00000132155 RAF1 ENSG00000169032 MAP2K1 H. sapiens SSL Slorth 0.944609 View
ENSG00000132155 RAF1 ENSG00000161202 DVL3 H. sapiens SDL Slorth 0.9446 View
ENSG00000107036 RIC1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.944586 View
ENSG00000132155 RAF1 ENSG00000166670 MMP10 H. sapiens SDL Slorth 0.944568 View
ENSG00000132155 RAF1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.944565 View
ENSG00000132155 RAF1 ENSG00000137309 HMGA1 H. sapiens SSL Slorth 0.944554 View
ENSG00000132155 RAF1 ENSG00000283094 PTEN H. sapiens SDL Slorth 0.944519 View
ENSG00000082258 CCNT2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.944516 View
ENSG00000132155 RAF1 ENSG00000198356 ASNA1 H. sapiens SSL Slorth 0.944494 View
ENSG00000058272 PPP1R12A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.944336 View
ENSG00000132155 RAF1 ENSG00000163435 ELF3 H. sapiens SDL Slorth 0.944334 View
ENSG00000132155 RAF1 ENSG00000197943 PLCG2 H. sapiens SSL Slorth 0.94433 View
ENSG00000132155 RAF1 ENSG00000163914 RHO H. sapiens SDL Slorth 0.944317 View
ENSG00000132155 RAF1 ENSG00000176749 CDK5R1 H. sapiens SSL Slorth 0.94406 View
ENSG00000024048 UBR2 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.943931 View
ENSG00000124571 XPO5 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.943931 View
ENSG00000132155 RAF1 ENSG00000162924 REL H. sapiens SSL Slorth 0.94391 View
ENSG00000132155 RAF1 ENSG00000166341 DCHS1 H. sapiens SDL Slorth 0.943867 View
ENSG00000109062 SLC9A3R1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.943845 View
ENSG00000103769 RAB11A ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.94382 View
ENSG00000132155 RAF1 ENSG00000168556 ING2 H. sapiens SSL Slorth 0.9438 View
ENSG00000132155 RAF1 ENSG00000173933 RBM4 H. sapiens SSL Slorth 0.943729 View
ENSG00000132155 RAF1 ENSG00000172115 CYCS H. sapiens SSL Slorth 0.943696 View
ENSG00000132155 RAF1 ENSG00000183020 AP2A2 H. sapiens SSL Slorth 0.943687 View
ENSG00000132155 RAF1 ENSG00000157554 ERG H. sapiens SSL Slorth 0.943637 View
ENSG00000132155 RAF1 ENSG00000196628 TCF4 H. sapiens SDL Slorth 0.943572 View
ENSG00000132155 RAF1 ENSG00000176974 SHMT1 H. sapiens SSL Slorth 0.943568 View
ENSG00000132155 RAF1 ENSG00000184634 MED12 H. sapiens SDL Slorth 0.94352 View
ENSG00000083750 RRAGB ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.943492 View