RAF1 - TCF4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
TCF4	ENSG00000196628	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, TFIIB-class binding TFIIB-class transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding identical protein binding protein homodimerization activity bHLH transcription factor binding protein heterodimerization activity E-box binding	hlh-2 (C. elegans)