RAF1

ENSG00000132155 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019899 enzyme binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor

Diseases

Disease Name
pilocytic astrocytoma
prostate

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000093000 NUP50 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.948721 View
ENSG00000132155 RAF1 ENSG00000189403 HMGB1 H. sapiens SSL Slorth 0.948712 View
ENSG00000123358 NR4A1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.948703 View
ENSG00000132155 RAF1 ENSG00000141968 VAV1 H. sapiens SDL Slorth 0.94865 View
ENSG00000132155 RAF1 ENSG00000172175 MALT1 H. sapiens SSL Slorth 0.948639 View
ENSG00000132155 RAF1 ENSG00000254995 STX16-NPEPL1 H. sapiens SDL Slorth 0.948622 View
ENSG00000132155 RAF1 ENSG00000205250 E2F4 H. sapiens SDL Slorth 0.948604 View
ENSG00000132155 RAF1 ENSG00000143756 FBXO28 H. sapiens SDL Slorth 0.948587 View
ENSG00000132155 RAF1 ENSG00000174013 FBXO45 H. sapiens SDL Slorth 0.948587 View
ENSG00000132155 RAF1 ENSG00000136273 HUS1 H. sapiens SSL Slorth 0.948556 View
ENSG00000132155 RAF1 ENSG00000166501 PRKCB H. sapiens SDL Slorth 0.948537 View
ENSG00000132155 RAF1 ENSG00000162409 PRKAA2 H. sapiens SSL Slorth 0.94848 View
ENSG00000094631 HDAC6 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.948431 View
ENSG00000101665 SMAD7 ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.948323 View
ENSG00000132155 RAF1 ENSG00000163931 TKT H. sapiens SSL Slorth 0.948284 View
ENSG00000132155 RAF1 ENSG00000132906 CASP9 H. sapiens SSL Slorth 0.948254 View
ENSG00000132155 RAF1 ENSG00000132388 UBE2G1 H. sapiens SDL Slorth 0.948199 View
ENSG00000001626 CFTR ENSG00000132155 RAF1 H. sapiens SSL Slorth 0.948146 View
ENSG00000132155 RAF1 ENSG00000136826 KLF4 H. sapiens SDL Slorth 0.948123 View
ENSG00000101752 MIB1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.94809 View
ENSG00000132155 RAF1 ENSG00000184979 USP18 H. sapiens SSL Slorth 0.948025 View
ENSG00000132155 RAF1 ENSG00000160445 ZER1 H. sapiens SDL Slorth 0.947964 View
ENSG00000132155 RAF1 ENSG00000198668 CALM1 H. sapiens SDL Slorth 0.947951 View
ENSG00000132155 RAF1 ENSG00000133895 MEN1 H. sapiens SSL Slorth 0.947886 View
ENSG00000124181 PLCG1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.947877 View
ENSG00000132155 RAF1 ENSG00000161203 AP2M1 H. sapiens SSL Slorth 0.94781 View
ENSG00000132155 RAF1 ENSG00000146425 DYNLT1 H. sapiens SDL Slorth 0.947807 View
ENSG00000132155 RAF1 ENSG00000150753 CCT5 H. sapiens SSL Slorth 0.947732 View
ENSG00000132155 RAF1 ENSG00000143751 SDE2 H. sapiens SDL Slorth 0.947687 View
ENSG00000122882 ECD ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.94768 View
ENSG00000132155 RAF1 ENSG00000157349 DDX19B H. sapiens SSL Slorth 0.947671 View
ENSG00000132155 RAF1 ENSG00000134899 ERCC5 H. sapiens SDL Slorth 0.947643 View
ENSG00000118007 STAG1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.947632 View
ENSG00000110719 TCIRG1 ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.94763 View
ENSG00000132155 RAF1 ENSG00000176102 CSTF3 H. sapiens SDL Slorth 0.947618 View
ENSG00000132155 RAF1 ENSG00000188419 CHM H. sapiens SDL Slorth 0.947606 View
ENSG00000132155 RAF1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.94758 View
ENSG00000132155 RAF1 ENSG00000140992 PDPK1 H. sapiens SDL Slorth 0.947558 View
ENSG00000078061 ARAF ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.947462 View
ENSG00000132155 RAF1 ENSG00000184900 SUMO3 H. sapiens SDL Slorth 0.947395 View