CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000143514 TP53BP2 H. sapiens SSL Slorth 0.938792 View
ENSG00000074319 TSG101 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.938635 View
ENSG00000135446 CDK4 ENSG00000162775 RBM15 H. sapiens SDL Slorth 0.938254 View
ENSG00000134982 APC ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.938163 View
ENSG00000078043 PIAS2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.93797 View
ENSG00000026103 FAS ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.937914 View
ENSG00000067606 PRKCZ ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.937905 View
ENSG00000108094 CUL2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.937764 View
ENSG00000130177 CDC16 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.937718 View
ENSG00000076242 MLH1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.937661 View
ENSG00000114503 NCBP2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.937651 View
ENSG00000135446 CDK4 ENSG00000138376 BARD1 H. sapiens SDL Slorth 0.937594 View
ENSG00000118007 STAG1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.937496 View
ENSG00000135446 CDK4 ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.937478 View
ENSG00000135446 CDK4 ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.937414 View
ENSG00000135446 CDK4 ENSG00000172531 PPP1CA H. sapiens SDL Slorth 0.937387 View
ENSG00000080986 NDC80 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.937315 View
ENSG00000135446 CDK4 ENSG00000138395 CDK15 H. sapiens SDL Slorth 0.937278 View
ENSG00000111262 KCNA1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.93716 View
ENSG00000067141 NEO1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.93716 View
ENSG00000135446 CDK4 ENSG00000182866 LCK H. sapiens SSL Slorth 0.937053 View
ENSG00000135446 CDK4 ENSG00000178997 EXD1 H. sapiens SDL Slorth 0.936915 View
ENSG00000135446 CDK4 ENSG00000136273 HUS1 H. sapiens SDL Slorth 0.936835 View
ENSG00000133101 CCNA1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.936669 View
ENSG00000114742 WDR48 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.936664 View
ENSG00000105011 ASF1B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.936498 View
ENSG00000135446 CDK4 ENSG00000140600 SH3GL3 H. sapiens SDL Slorth 0.936431 View
ENSG00000125967 NECAB3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.936335 View
ENSG00000001167 NFYA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.936051 View
ENSG00000117399 CDC20 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.936025 View
ENSG00000135446 CDK4 ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.936 View
ENSG00000102781 KATNAL1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.935992 View
ENSG00000135446 CDK4 ENSG00000172936 MYD88 H. sapiens SSL Slorth 0.935971 View
ENSG00000135446 CDK4 ENSG00000167670 CHAF1A H. sapiens SDL Slorth 0.935901 View
ENSG00000135446 CDK4 ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.935786 View
ENSG00000135446 CDK4 ENSG00000213923 CSNK1E H. sapiens SDL Slorth 0.935774 View
ENSG00000133740 E2F5 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.935697 View
ENSG00000125618 PAX8 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.935692 View
ENSG00000075785 RAB7A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.935657 View
ENSG00000096968 JAK2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.935476 View