CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000103479 RBL2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.941746 View
ENSG00000135446 CDK4 ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.941656 View
ENSG00000135446 CDK4 ENSG00000141564 RPTOR H. sapiens SSL Slorth 0.941486 View
ENSG00000070718 AP3M2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.941454 View
ENSG00000135446 CDK4 ENSG00000154237 LRRK1 H. sapiens SDL Slorth 0.941383 View
ENSG00000117748 RPA2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.941317 View
ENSG00000135446 CDK4 ENSG00000179262 RAD23A H. sapiens SSL Slorth 0.941213 View
ENSG00000134871 COL4A2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.941164 View
ENSG00000127329 PTPRB ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.941164 View
ENSG00000135446 CDK4 ENSG00000178573 MAF H. sapiens SDL Slorth 0.941103 View
ENSG00000135446 CDK4 ENSG00000186575 NF2 H. sapiens SDL Slorth 0.941036 View
ENSG00000004897 CDC27 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.940753 View
ENSG00000001626 CFTR ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.940728 View
ENSG00000100297 MCM5 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.940639 View
ENSG00000066923 STAG3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.940463 View
ENSG00000075089 ACTR6 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.940438 View
ENSG00000130332 LSM7 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.940278 View
ENSG00000135446 CDK4 ENSG00000171621 SPSB1 H. sapiens SDL Slorth 0.940226 View
ENSG00000135446 CDK4 ENSG00000254772 EEF1G H. sapiens SSL Slorth 0.940138 View
ENSG00000135446 CDK4 ENSG00000158290 CUL4B H. sapiens SSL Slorth 0.940035 View
ENSG00000135446 CDK4 ENSG00000149554 CHEK1 H. sapiens SDL Slorth 0.939972 View
ENSG00000135446 CDK4 ENSG00000175305 CCNE2 H. sapiens SDL Slorth 0.939931 View
ENSG00000108953 YWHAE ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.93992 View
ENSG00000135446 CDK4 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.939549 View
ENSG00000135446 CDK4 ENSG00000163743 RCHY1 H. sapiens SSL Slorth 0.939485 View
ENSG00000135446 CDK4 ENSG00000163041 H3F3A H. sapiens SSL Slorth 0.939439 View
ENSG00000050820 BCAR1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.939412 View
ENSG00000135446 CDK4 ENSG00000160789 LMNA H. sapiens SDL Slorth 0.939302 View
ENSG00000090889 KIF4A ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.939261 View
ENSG00000132669 RIN2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.939096 View
ENSG00000118503 TNFAIP3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.939093 View
ENSG00000117222 RBBP5 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.939071 View
ENSG00000135446 CDK4 ENSG00000148660 CAMK2G H. sapiens SDL Slorth 0.939035 View
ENSG00000135446 CDK4 ENSG00000136237 RAPGEF5 H. sapiens SDL Slorth 0.938926 View
ENSG00000094880 CDC23 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.938905 View
ENSG00000135446 CDK4 ENSG00000167552 TUBA1A H. sapiens SDL Slorth 0.938848 View
ENSG00000135446 CDK4 ENSG00000163947 ARHGEF3 H. sapiens SDL Slorth 0.938823 View
ENSG00000120656 TAF12 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.938818 View
ENSG00000135446 CDK4 ENSG00000164362 TERT H. sapiens SSL Slorth 0.9388 View
ENSG00000079337 RAPGEF3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.938799 View