CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000135446 CDK4 ENSG00000196218 RYR1 H. sapiens SDL Slorth 0.932388 View
ENSG00000125656 CLPP ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.932295 View
ENSG00000109971 HSPA8 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.932147 View
ENSG00000070404 FSTL3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.932014 View
ENSG00000085840 ORC1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.931917 View
ENSG00000135446 CDK4 ENSG00000138795 LEF1 H. sapiens SDL Slorth 0.931786 View
ENSG00000135446 CDK4 ENSG00000142875 PRKACB H. sapiens SDL Slorth 0.931698 View
ENSG00000135446 CDK4 ENSG00000168556 ING2 H. sapiens SSL Slorth 0.931648 View
ENSG00000135446 CDK4 ENSG00000168453 HR H. sapiens SDL Slorth 0.931632 View
ENSG00000135446 CDK4 ENSG00000187109 NAP1L1 H. sapiens SSL Slorth 0.93154 View
ENSG00000135446 CDK4 ENSG00000180176 TH H. sapiens SDL Slorth 0.931524 View
ENSG00000103035 PSMD7 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.931515 View
ENSG00000135446 CDK4 ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.931464 View
ENSG00000048540 LMO3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.931426 View
ENSG00000110107 PRPF19 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.931425 View
ENSG00000101460 MAP1LC3A ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.931365 View
ENSG00000127445 PIN1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.931288 View
ENSG00000135446 CDK4 ENSG00000196305 IARS H. sapiens SSL Slorth 0.931181 View
ENSG00000114315 HES1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.931128 View
ENSG00000135446 CDK4 ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.931109 View
ENSG00000135446 CDK4 ENSG00000169696 ASPSCR1 H. sapiens SDL Slorth 0.931079 View
ENSG00000135446 CDK4 ENSG00000173207 CKS1B H. sapiens SDL Slorth 0.931016 View
ENSG00000073614 KDM5A ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.930956 View
ENSG00000118689 FOXO3 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.93094 View
ENSG00000061918 GUCY1B3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.93084 View
ENSG00000135446 CDK4 ENSG00000163904 SENP2 H. sapiens SDL Slorth 0.930557 View
ENSG00000135446 CDK4 ENSG00000163960 UBXN7 H. sapiens SSL Slorth 0.930505 View
ENSG00000135446 CDK4 ENSG00000153234 NR4A2 H. sapiens SDL Slorth 0.930356 View
ENSG00000102974 CTCF ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.930326 View
ENSG00000016082 ISL1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.930245 View
ENSG00000135446 CDK4 ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.930173 View
ENSG00000130766 SESN2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.930166 View
ENSG00000135446 CDK4 ENSG00000255112 CHMP1B H. sapiens SDL Slorth 0.930125 View
ENSG00000135446 CDK4 ENSG00000159259 CHAF1B H. sapiens SDL Slorth 0.930005 View
ENSG00000106327 TFR2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929815 View
ENSG00000135312 HTR1B ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929815 View
ENSG00000117400 MPL ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929815 View
ENSG00000085832 EPS15 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.929759 View
ENSG00000077092 RARB ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929597 View
ENSG00000072422 RHOBTB1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929588 View