CTCF - CDK4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CTCF	ENSG00000102974	endometrial breast head and neck cancer	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding zinc ion binding chromatin insulator sequence binding sequence-specific DNA binding transcription regulatory region DNA binding transcription regulatory region sequence-specific DNA binding	CTCF (D. melanogaster)
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)