CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000049323 LTBP1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.935427 View
ENSG00000112319 EYA4 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.935386 View
ENSG00000115507 OTX1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.935386 View
ENSG00000135446 CDK4 ENSG00000163932 PRKCD H. sapiens SDL Slorth 0.93512 View
ENSG00000135446 CDK4 ENSG00000180370 PAK2 H. sapiens SDL Slorth 0.935079 View
ENSG00000102034 ELF4 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.935041 View
ENSG00000112242 E2F3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.934794 View
ENSG00000007264 MATK ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.934638 View
ENSG00000135446 CDK4 ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.934593 View
ENSG00000135446 CDK4 ENSG00000136603 SKIL H. sapiens SSL Slorth 0.934535 View
ENSG00000066455 GOLGA5 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.934492 View
ENSG00000117625 RCOR3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.934421 View
ENSG00000070831 CDC42 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.934408 View
ENSG00000126457 PRMT1 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.9344 View
ENSG00000135446 CDK4 ENSG00000151422 FER H. sapiens SDL Slorth 0.934327 View
ENSG00000135446 CDK4 ENSG00000141738 GRB7 H. sapiens SDL Slorth 0.934308 View
ENSG00000135446 CDK4 ENSG00000147140 NONO H. sapiens SDL Slorth 0.934229 View
ENSG00000135446 CDK4 ENSG00000136997 MYC H. sapiens SDL Slorth 0.934085 View
ENSG00000135446 CDK4 ENSG00000168421 RHOH H. sapiens SDL Slorth 0.933944 View
ENSG00000071051 NCK2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.933933 View
ENSG00000061938 TNK2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.933907 View
ENSG00000085276 MECOM ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.933896 View
ENSG00000125968 ID1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.933864 View
ENSG00000051180 RAD51 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.933742 View
ENSG00000135446 CDK4 ENSG00000198087 CD2AP H. sapiens SSL Slorth 0.933723 View
ENSG00000135446 CDK4 ENSG00000185513 L3MBTL1 H. sapiens SDL Slorth 0.933685 View
ENSG00000092421 SEMA6A ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.933625 View
ENSG00000128271 ADORA2A ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.933493 View
ENSG00000041353 RAB27B ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.933493 View
ENSG00000125810 CD93 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.933493 View
ENSG00000125740 FOSB ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.933145 View
ENSG00000107282 APBA1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.932924 View
ENSG00000135446 CDK4 ENSG00000175390 EIF3F H. sapiens SSL Slorth 0.932848 View
ENSG00000050748 MAPK9 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.932786 View
ENSG00000101811 CSTF2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.932638 View
ENSG00000135446 CDK4 ENSG00000136807 CDK9 H. sapiens SSL Slorth 0.932617 View
ENSG00000115216 NRBP1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.932561 View
ENSG00000135446 CDK4 ENSG00000160803 UBQLN4 H. sapiens SDL Slorth 0.932539 View
ENSG00000135446 CDK4 ENSG00000175766 EIF4E1B H. sapiens SDL Slorth 0.932508 View
ENSG00000115808 STRN ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.932507 View