CDK4

ENSG00000135446 - H. sapiens

Pathways

Go term Description
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
GO:0030332 cyclin binding
GO:0032403 protein complex binding
GO:0004674 protein serine/threonine kinase activity

Drugs

Drug name Description
PALBOCICLIB CDK4/cyclin D1 inhibitor

Diseases

Disease Name
melanoma

Orthologs

Gene Organism
CDC28 S. cerevisiae
cdk-4 C. elegans
Cdk4 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000072422 RHOBTB1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929588 View
ENSG00000044574 HSPA5 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.929518 View
ENSG00000123600 METTL8 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929515 View
ENSG00000070476 ZXDC ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929506 View
ENSG00000010671 BTK ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929503 View
ENSG00000135446 CDK4 ENSG00000167005 NUDT21 H. sapiens SSL Slorth 0.929491 View
ENSG00000115592 PRKAG3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.929425 View
ENSG00000135446 CDK4 ENSG00000170836 PPM1D H. sapiens SDL Slorth 0.929316 View
ENSG00000135446 CDK4 ENSG00000135476 ESPL1 H. sapiens SSL Slorth 0.929187 View
ENSG00000064995 TAF11 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.928863 View
ENSG00000135446 CDK4 ENSG00000176248 ANAPC2 H. sapiens SDL Slorth 0.928822 View
ENSG00000106263 EIF3B ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.928717 View
ENSG00000006451 RALA ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.928696 View
ENSG00000132326 PER2 ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.928662 View
ENSG00000135446 CDK4 ENSG00000146094 DOK3 H. sapiens SDL Slorth 0.928621 View
ENSG00000135446 CDK4 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.92858 View
ENSG00000135446 CDK4 ENSG00000166477 LEO1 H. sapiens SDL Slorth 0.928488 View
ENSG00000135446 CDK4 ENSG00000164022 AIMP1 H. sapiens SSL Slorth 0.928433 View
ENSG00000135446 CDK4 ENSG00000141552 ANAPC11 H. sapiens SSL Slorth 0.928313 View
ENSG00000120500 ARR3 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.928123 View
ENSG00000051382 PIK3CB ENSG00000135446 CDK4 H. sapiens SSL Slorth 0.927873 View
ENSG00000104140 RHOV ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.927847 View
ENSG00000108773 KAT2A ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.927847 View
ENSG00000105204 DYRK1B ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.927824 View
ENSG00000080224 EPHA6 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.927787 View
ENSG00000135446 CDK4 ENSG00000168066 SF1 H. sapiens SSL Slorth 0.92776 View
ENSG00000126785 RHOJ ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.927704 View
ENSG00000114554 PLXNA1 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.927553 View
ENSG00000135446 CDK4 ENSG00000157933 SKI H. sapiens SDL Slorth 0.927532 View
ENSG00000075340 ADD2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.92745 View
ENSG00000029639 TFB1M ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.927382 View
ENSG00000135446 CDK4 ENSG00000147316 MCPH1 H. sapiens SDL Slorth 0.927364 View
ENSG00000135446 CDK4 ENSG00000135476 ESPL1 H. sapiens SDL Slorth 0.927355 View
ENSG00000135446 CDK4 ENSG00000137486 ARRB1 H. sapiens SDL Slorth 0.927223 View
ENSG00000135446 CDK4 ENSG00000166341 DCHS1 H. sapiens SDL Slorth 0.927183 View
ENSG00000064489 BORCS8-MEF2B ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.927155 View
ENSG00000135446 CDK4 ENSG00000148606 POLR3A H. sapiens SSL Slorth 0.926939 View
ENSG00000106588 PSMA2 ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.926664 View
ENSG00000106546 AHR ENSG00000135446 CDK4 H. sapiens SDL Slorth 0.92661 View
ENSG00000135446 CDK4 ENSG00000163161 ERCC3 H. sapiens SSL Slorth 0.926597 View