HES1 - CDK4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HES1	ENSG00000114315	No diseases in record	No drugs in record	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein homodimerization activity histone deacetylase binding sequence-specific DNA binding chaperone binding N-box binding oxysterol binding lipid binding sterol transporter activity	lin-22 (C. elegans) h (D. melanogaster) dpn (D. melanogaster)
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)