APC - CDK4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
APC	ENSG00000134982	colorectal pancreatic desmoid hepatoblastoma glioma other CNS	No drugs in record	protein binding beta-catenin binding microtubule binding protein kinase regulator activity protein kinase binding gamma-catenin binding microtubule plus-end binding cadherin binding	apr-1 (C. elegans) Apc2 (D. melanogaster) Apc (D. melanogaster)
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)