ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000176444 CLK2 H. sapiens SDL Slorth 0.972871 View
ENSG00000097007 ABL1 ENSG00000115053 NCL H. sapiens SSL Slorth 0.972863 View
ENSG00000097007 ABL1 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.972843 View
ENSG00000097007 ABL1 ENSG00000244687 UBE2V1 H. sapiens SDL Slorth 0.972835 View
ENSG00000097007 ABL1 ENSG00000114423 CBLB H. sapiens SSL Slorth 0.972819 View
ENSG00000097007 ABL1 ENSG00000110330 BIRC2 H. sapiens SSL Slorth 0.972816 View
ENSG00000097007 ABL1 ENSG00000151067 CACNA1C H. sapiens SDL Slorth 0.972793 View
ENSG00000013441 CLK1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.972791 View
ENSG00000097007 ABL1 ENSG00000124782 RREB1 H. sapiens SDL Slorth 0.972784 View
ENSG00000097007 ABL1 ENSG00000101972 STAG2 H. sapiens SDL Slorth 0.972768 View
ENSG00000097007 ABL1 ENSG00000125378 BMP4 H. sapiens SDL Slorth 0.972717 View
ENSG00000097007 ABL1 ENSG00000161202 DVL3 H. sapiens SDL Slorth 0.972711 View
ENSG00000097007 ABL1 ENSG00000135018 UBQLN1 H. sapiens SSL Slorth 0.972654 View
ENSG00000097007 ABL1 ENSG00000171793 CTPS1 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000198265 HELZ H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000168827 GFM1 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000120756 PLS1 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000143545 RAB13 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000115657 ABCB6 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000123983 ACSL3 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000105409 ATP1A3 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000099992 TBC1D10A H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000159733 ZFYVE28 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000173914 RBM4B H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000138031 ADCY3 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000152904 GGPS1 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000108523 RNF167 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000134644 PUM1 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000101608 MYL12A H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000139190 VAMP1 H. sapiens SDL Slorth 0.972629 View
ENSG00000097007 ABL1 ENSG00000142675 CNKSR1 H. sapiens SDL Slorth 0.972562 View
ENSG00000097007 ABL1 ENSG00000099804 CDC34 H. sapiens SSL Slorth 0.972547 View
ENSG00000097007 ABL1 ENSG00000140307 GTF2A2 H. sapiens SDL Slorth 0.972507 View
ENSG00000097007 ABL1 ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.972504 View
ENSG00000097007 ABL1 ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.9725 View
ENSG00000097007 ABL1 ENSG00000198836 OPA1 H. sapiens SDL Slorth 0.972459 View
ENSG00000097007 ABL1 ENSG00000151532 VTI1A H. sapiens SDL Slorth 0.972437 View
ENSG00000097007 ABL1 ENSG00000186575 NF2 H. sapiens SSL Slorth 0.972422 View
ENSG00000097007 ABL1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.972407 View
ENSG00000097007 ABL1 ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.972404 View