ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000160445 ZER1 H. sapiens SSL Slorth 0.753173 View
ENSG00000097007 ABL1 ENSG00000101911 PRPS2 H. sapiens SSL Slorth 0.753065 View
ENSG00000097007 ABL1 ENSG00000140990 NDUFB10 H. sapiens SSL Slorth 0.752993 View
ENSG00000097007 ABL1 ENSG00000142945 KIF2C H. sapiens SSL Slorth 0.752877 View
ENSG00000097007 ABL1 ENSG00000185250 PPIL6 H. sapiens SSL Slorth 0.75266 View
ENSG00000097007 ABL1 ENSG00000204231 RXRB H. sapiens SSL Slorth 0.752323 View
ENSG00000097007 ABL1 ENSG00000171720 HDAC3 H. sapiens SSL Slorth 0.752099 View
ENSG00000097007 ABL1 ENSG00000182944 EWSR1 H. sapiens SSL Slorth 0.751843 View
ENSG00000075785 RAB7A ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.751553 View
ENSG00000097007 ABL1 ENSG00000173626 TRAPPC3L H. sapiens SSL Slorth 0.751533 View
ENSG00000097007 ABL1 ENSG00000179295 PTPN11 H. sapiens SSL Slorth 0.751268 View
ENSG00000097007 ABL1 ENSG00000185920 PTCH1 H. sapiens SSL Slorth 0.751117 View
ENSG00000097007 ABL1 ENSG00000152104 PTPN14 H. sapiens SSL Slorth 0.750895 View
ENSG00000097007 ABL1 ENSG00000104142 VPS18 H. sapiens SSL Slorth 0.750765 View