ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000146457 WTAP H. sapiens SSL Slorth 0.833027 View
ENSG00000097007 ABL1 ENSG00000117569 PTBP2 H. sapiens SSL Slorth 0.832009 View
ENSG00000097007 ABL1 ENSG00000179776 CDH5 H. sapiens SSL Slorth 0.83189 View
ENSG00000097007 ABL1 ENSG00000132964 CDK8 H. sapiens SSL Slorth 0.831789 View
ENSG00000097007 ABL1 ENSG00000100142 POLR2F H. sapiens SSL Slorth 0.831684 View
ENSG00000097007 ABL1 ENSG00000101384 JAG1 H. sapiens SSL Slorth 0.831491 View
ENSG00000097007 ABL1 ENSG00000130826 DKC1 H. sapiens SSL Slorth 0.831477 View
ENSG00000097007 ABL1 ENSG00000155876 RRAGA H. sapiens SSL Slorth 0.831136 View
ENSG00000097007 ABL1 ENSG00000170315 UBB H. sapiens SSL Slorth 0.830885 View
ENSG00000097007 ABL1 ENSG00000115232 ITGA4 H. sapiens SSL Slorth 0.830883 View
ENSG00000097007 ABL1 ENSG00000198382 UVRAG H. sapiens SSL Slorth 0.830356 View
ENSG00000097007 ABL1 ENSG00000123374 CDK2 H. sapiens SSL Slorth 0.830208 View
ENSG00000097007 ABL1 ENSG00000129562 DAD1 H. sapiens SSL Slorth 0.829958 View
ENSG00000097007 ABL1 ENSG00000132842 AP3B1 H. sapiens SSL Slorth 0.829864 View
ENSG00000097007 ABL1 ENSG00000197780 TAF13 H. sapiens SSL Slorth 0.829844 View
ENSG00000097007 ABL1 ENSG00000107186 MPDZ H. sapiens SSL Slorth 0.829772 View
ENSG00000085511 MAP3K4 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.829438 View
ENSG00000097007 ABL1 ENSG00000135250 SRPK2 H. sapiens SSL Slorth 0.829326 View
ENSG00000097007 ABL1 ENSG00000146535 GNA12 H. sapiens SSL Slorth 0.829294 View
ENSG00000097007 ABL1 ENSG00000126777 KTN1 H. sapiens SSL Slorth 0.829212 View
ENSG00000097007 ABL1 ENSG00000143171 RXRG H. sapiens SSL Slorth 0.829201 View
ENSG00000097007 ABL1 ENSG00000119707 RBM25 H. sapiens SSL Slorth 0.829172 View
ENSG00000097007 ABL1 ENSG00000145495 MARCH6 H. sapiens SSL Slorth 0.829038 View
ENSG00000097007 ABL1 ENSG00000147955 SIGMAR1 H. sapiens SSL Slorth 0.82894 View
ENSG00000097007 ABL1 ENSG00000108179 PPIF H. sapiens SSL Slorth 0.828573 View
ENSG00000049759 NEDD4L ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.828471 View
ENSG00000097007 ABL1 ENSG00000139505 MTMR6 H. sapiens SSL Slorth 0.828465 View
ENSG00000097007 ABL1 ENSG00000136143 SUCLA2 H. sapiens SSL Slorth 0.828092 View
ENSG00000097007 ABL1 ENSG00000151748 SAV1 H. sapiens SSL Slorth 0.828012 View
ENSG00000097007 ABL1 ENSG00000103111 MON1B H. sapiens SSL Slorth 0.827819 View
ENSG00000097007 ABL1 ENSG00000160691 SHC1 H. sapiens SSL Slorth 0.8276 View
ENSG00000097007 ABL1 ENSG00000111481 COPZ1 H. sapiens SSL Slorth 0.827488 View
ENSG00000097007 ABL1 ENSG00000132207 SLX1A H. sapiens SSL Slorth 0.827458 View
ENSG00000097007 ABL1 ENSG00000099940 SNAP29 H. sapiens SSL Slorth 0.827313 View
ENSG00000097007 ABL1 ENSG00000134910 STT3A H. sapiens SSL Slorth 0.826699 View
ENSG00000097007 ABL1 ENSG00000109929 SC5D H. sapiens SSL Slorth 0.826228 View
ENSG00000097007 ABL1 ENSG00000101361 NOP56 H. sapiens SSL Slorth 0.826218 View
ENSG00000097007 ABL1 ENSG00000137955 RABGGTB H. sapiens SSL Slorth 0.826206 View
ENSG00000097007 ABL1 ENSG00000167315 ACAA2 H. sapiens SSL Slorth 0.82603 View
ENSG00000097007 ABL1 ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.82562 View