ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000155660 PDIA4 H. sapiens SSL Slorth 0.856951 View
ENSG00000097007 ABL1 ENSG00000138190 EXOC6 H. sapiens SSL Slorth 0.856366 View
ENSG00000097007 ABL1 ENSG00000131165 CHMP1A H. sapiens SSL Slorth 0.856206 View
ENSG00000097007 ABL1 ENSG00000115310 RTN4 H. sapiens SSL Slorth 0.856083 View
ENSG00000097007 ABL1 ENSG00000177606 JUN H. sapiens SSL Slorth 0.855659 View
ENSG00000097007 ABL1 ENSG00000140416 TPM1 H. sapiens SSL Slorth 0.85557 View
ENSG00000097007 ABL1 ENSG00000103769 RAB11A H. sapiens SSL Slorth 0.855256 View
ENSG00000097007 ABL1 ENSG00000213983 AP1G2 H. sapiens SSL Slorth 0.855126 View
ENSG00000097007 ABL1 ENSG00000112062 MAPK14 H. sapiens SSL Slorth 0.854935 View
ENSG00000097007 ABL1 ENSG00000110172 CHORDC1 H. sapiens SSL Slorth 0.854896 View
ENSG00000097007 ABL1 ENSG00000185624 P4HB H. sapiens SSL Slorth 0.854721 View
ENSG00000097007 ABL1 ENSG00000139726 DENR H. sapiens SSL Slorth 0.854542 View
ENSG00000097007 ABL1 ENSG00000117614 SYF2 H. sapiens SSL Slorth 0.854353 View
ENSG00000097007 ABL1 ENSG00000137413 TAF8 H. sapiens SSL Slorth 0.854353 View
ENSG00000097007 ABL1 ENSG00000197114 ZGPAT H. sapiens SSL Slorth 0.854071 View
ENSG00000097007 ABL1 ENSG00000147669 POLR2K H. sapiens SSL Slorth 0.853864 View
ENSG00000097007 ABL1 ENSG00000141959 PFKL H. sapiens SSL Slorth 0.853801 View
ENSG00000097007 ABL1 ENSG00000147224 PRPS1 H. sapiens SSL Slorth 0.853801 View
ENSG00000097007 ABL1 ENSG00000152556 PFKM H. sapiens SSL Slorth 0.853801 View
ENSG00000097007 ABL1 ENSG00000179094 PER1 H. sapiens SSL Slorth 0.853515 View
ENSG00000097007 ABL1 ENSG00000163513 TGFBR2 H. sapiens SSL Slorth 0.853228 View
ENSG00000097007 ABL1 ENSG00000126524 SBDS H. sapiens SSL Slorth 0.853169 View
ENSG00000097007 ABL1 ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.85258 View
ENSG00000097007 ABL1 ENSG00000185236 RAB11B H. sapiens SSL Slorth 0.852482 View
ENSG00000094916 CBX5 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.852306 View
ENSG00000097007 ABL1 ENSG00000100911 PSME2 H. sapiens SSL Slorth 0.852269 View
ENSG00000097007 ABL1 ENSG00000135930 EIF4E2 H. sapiens SSL Slorth 0.852261 View
ENSG00000097007 ABL1 ENSG00000183431 SF3A3 H. sapiens SSL Slorth 0.852168 View
ENSG00000097007 ABL1 ENSG00000112096 SOD2 H. sapiens SSL Slorth 0.852035 View
ENSG00000097007 ABL1 ENSG00000169439 SDC2 H. sapiens SSL Slorth 0.851945 View
ENSG00000097007 ABL1 ENSG00000179091 CYC1 H. sapiens SSL Slorth 0.851759 View
ENSG00000097007 ABL1 ENSG00000118046 STK11 H. sapiens SSL Slorth 0.851713 View
ENSG00000097007 ABL1 ENSG00000154174 TOMM70 H. sapiens SSL Slorth 0.851422 View
ENSG00000097007 ABL1 ENSG00000197275 RAD54B H. sapiens SSL Slorth 0.850862 View
ENSG00000097007 ABL1 ENSG00000160087 UBE2J2 H. sapiens SSL Slorth 0.850596 View
ENSG00000097007 ABL1 ENSG00000166949 SMAD3 H. sapiens SSL Slorth 0.849727 View
ENSG00000097007 ABL1 ENSG00000213079 SCAF8 H. sapiens SSL Slorth 0.8496 View
ENSG00000097007 ABL1 ENSG00000158987 RAPGEF6 H. sapiens SSL Slorth 0.849227 View
ENSG00000097007 ABL1 ENSG00000137171 KLC4 H. sapiens SSL Slorth 0.849132 View
ENSG00000097007 ABL1 ENSG00000143473 KCNH1 H. sapiens SSL Slorth 0.848742 View