ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000174996 KLC2 H. sapiens SSL Slorth 0.864646 View
ENSG00000097007 ABL1 ENSG00000164941 INTS8 H. sapiens SSL Slorth 0.864611 View
ENSG00000097007 ABL1 ENSG00000157227 MMP14 H. sapiens SSL Slorth 0.864586 View
ENSG00000097007 ABL1 ENSG00000160868 CYP3A4 H. sapiens SSL Slorth 0.864544 View
ENSG00000097007 ABL1 ENSG00000140403 DNAJA4 H. sapiens SSL Slorth 0.864247 View
ENSG00000094880 CDC23 ENSG00000097007 ABL1 H. sapiens SSL Slorth 0.864203 View
ENSG00000097007 ABL1 ENSG00000280548 FBL H. sapiens SSL Slorth 0.864027 View
ENSG00000097007 ABL1 ENSG00000106089 STX1A H. sapiens SSL Slorth 0.863795 View
ENSG00000097007 ABL1 ENSG00000170881 RNF139 H. sapiens SSL Slorth 0.86375 View
ENSG00000097007 ABL1 ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.863494 View
ENSG00000097007 ABL1 ENSG00000106299 WASL H. sapiens SSL Slorth 0.863448 View
ENSG00000097007 ABL1 ENSG00000134717 BTF3L4 H. sapiens SSL Slorth 0.863111 View
ENSG00000097007 ABL1 ENSG00000114302 PRKAR2A H. sapiens SSL Slorth 0.863067 View
ENSG00000097007 ABL1 ENSG00000109458 GAB1 H. sapiens SSL Slorth 0.862674 View
ENSG00000097007 ABL1 ENSG00000131023 LATS1 H. sapiens SSL Slorth 0.862589 View
ENSG00000097007 ABL1 ENSG00000122025 FLT3 H. sapiens SSL Slorth 0.862382 View
ENSG00000097007 ABL1 ENSG00000132664 POLR3F H. sapiens SSL Slorth 0.862201 View
ENSG00000097007 ABL1 ENSG00000161638 ITGA5 H. sapiens SSL Slorth 0.862055 View
ENSG00000097007 ABL1 ENSG00000163541 SUCLG1 H. sapiens SSL Slorth 0.861843 View
ENSG00000097007 ABL1 ENSG00000197930 ERO1A H. sapiens SSL Slorth 0.861649 View
ENSG00000097007 ABL1 ENSG00000100028 SNRPD3 H. sapiens SSL Slorth 0.861306 View
ENSG00000097007 ABL1 ENSG00000140443 IGF1R H. sapiens SSL Slorth 0.861005 View
ENSG00000097007 ABL1 ENSG00000188612 SUMO2 H. sapiens SSL Slorth 0.860879 View
ENSG00000097007 ABL1 ENSG00000131263 RLIM H. sapiens SSL Slorth 0.860717 View
ENSG00000097007 ABL1 ENSG00000178184 PARD6G H. sapiens SSL Slorth 0.860571 View
ENSG00000097007 ABL1 ENSG00000100697 DICER1 H. sapiens SSL Slorth 0.86057 View
ENSG00000097007 ABL1 ENSG00000178028 DMAP1 H. sapiens SSL Slorth 0.86048 View
ENSG00000097007 ABL1 ENSG00000138175 ARL3 H. sapiens SSL Slorth 0.859754 View
ENSG00000097007 ABL1 ENSG00000115942 ORC2 H. sapiens SSL Slorth 0.859527 View
ENSG00000097007 ABL1 ENSG00000145782 ATG12 H. sapiens SSL Slorth 0.859375 View
ENSG00000097007 ABL1 ENSG00000123975 CKS2 H. sapiens SSL Slorth 0.859087 View
ENSG00000097007 ABL1 ENSG00000120805 ARL1 H. sapiens SSL Slorth 0.858895 View
ENSG00000097007 ABL1 ENSG00000103365 GGA2 H. sapiens SSL Slorth 0.8584 View
ENSG00000097007 ABL1 ENSG00000131508 UBE2D2 H. sapiens SSL Slorth 0.857917 View
ENSG00000097007 ABL1 ENSG00000205220 PSMB10 H. sapiens SSL Slorth 0.85787 View
ENSG00000097007 ABL1 ENSG00000203668 CHML H. sapiens SSL Slorth 0.857811 View
ENSG00000097007 ABL1 ENSG00000177879 AP3S1 H. sapiens SSL Slorth 0.857734 View
ENSG00000097007 ABL1 ENSG00000255150 EID3 H. sapiens SSL Slorth 0.857582 View
ENSG00000097007 ABL1 ENSG00000131381 RBSN H. sapiens SSL Slorth 0.857579 View
ENSG00000097007 ABL1 ENSG00000198380 GFPT1 H. sapiens SSL Slorth 0.857223 View