ABL1 - PTCH1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
PTCH1	ENSG00000185920	skin basal cell medulloblastoma	No drugs in record	patched binding smoothened binding protein binding hedgehog receptor activity heparin binding cholesterol binding cyclin binding protein complex binding hedgehog family protein binding	NCR1 (S. cerevisiae) ptc-1 (C. elegans) ptc-3 (C. elegans) ptc-2 (C. elegans) ptc (D. melanogaster)