ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000167985 SDHAF2 H. sapiens SDL Slorth 0.975753 View
ENSG00000011132 APBA3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.975733 View
ENSG00000097007 ABL1 ENSG00000128059 PPAT H. sapiens SDL Slorth 0.975718 View
ENSG00000097007 ABL1 ENSG00000183856 IQGAP3 H. sapiens SDL Slorth 0.975718 View
ENSG00000097007 ABL1 ENSG00000105647 PIK3R2 H. sapiens SDL Slorth 0.975718 View
ENSG00000097007 ABL1 ENSG00000132361 CLUH H. sapiens SDL Slorth 0.975718 View
ENSG00000097007 ABL1 ENSG00000137270 GCM1 H. sapiens SDL Slorth 0.975717 View
ENSG00000004975 DVL2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.975701 View
ENSG00000097007 ABL1 ENSG00000185359 HGS H. sapiens SDL Slorth 0.975696 View
ENSG00000097007 ABL1 ENSG00000105656 ELL H. sapiens SDL Slorth 0.975666 View
ENSG00000097007 ABL1 ENSG00000168078 PBK H. sapiens SDL Slorth 0.975551 View
ENSG00000097007 ABL1 ENSG00000136273 HUS1 H. sapiens SDL Slorth 0.975522 View
ENSG00000097007 ABL1 ENSG00000130479 MAP1S H. sapiens SDL Slorth 0.975517 View
ENSG00000097007 ABL1 ENSG00000126883 NUP214 H. sapiens SDL Slorth 0.975463 View
ENSG00000097007 ABL1 ENSG00000108469 RECQL5 H. sapiens SDL Slorth 0.975442 View
ENSG00000097007 ABL1 ENSG00000145632 PLK2 H. sapiens SDL Slorth 0.975438 View
ENSG00000097007 ABL1 ENSG00000106993 CDC37L1 H. sapiens SDL Slorth 0.975438 View
ENSG00000097007 ABL1 ENSG00000153201 RANBP2 H. sapiens SSL Slorth 0.975392 View
ENSG00000073060 SCARB1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.975384 View
ENSG00000097007 ABL1 ENSG00000121774 KHDRBS1 H. sapiens SDL Slorth 0.975377 View
ENSG00000097007 ABL1 ENSG00000150991 UBC H. sapiens SDL Slorth 0.975366 View
ENSG00000076928 ARHGEF1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.975362 View
ENSG00000097007 ABL1 ENSG00000119396 RAB14 H. sapiens SDL Slorth 0.975306 View
ENSG00000097007 ABL1 ENSG00000122692 SMU1 H. sapiens SDL Slorth 0.975298 View
ENSG00000097007 ABL1 ENSG00000169813 HNRNPF H. sapiens SSL Slorth 0.975256 View
ENSG00000097007 ABL1 ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.975249 View
ENSG00000097007 ABL1 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.975233 View
ENSG00000010818 HIVEP2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.975224 View
ENSG00000064933 PMS1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.975203 View
ENSG00000097007 ABL1 ENSG00000177565 TBL1XR1 H. sapiens SDL Slorth 0.975179 View
ENSG00000097007 ABL1 ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.975175 View
ENSG00000002834 LASP1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.975169 View
ENSG00000097007 ABL1 ENSG00000162924 REL H. sapiens SDL Slorth 0.975115 View
ENSG00000097007 ABL1 ENSG00000143473 KCNH1 H. sapiens SDL Slorth 0.975098 View
ENSG00000076344 RGS11 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.975094 View
ENSG00000097007 ABL1 ENSG00000124216 SNAI1 H. sapiens SSL Slorth 0.975092 View
ENSG00000097007 ABL1 ENSG00000126561 STAT5A H. sapiens SSL Slorth 0.975028 View
ENSG00000097007 ABL1 ENSG00000103111 MON1B H. sapiens SDL Slorth 0.975016 View
ENSG00000073921 PICALM ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.974984 View
ENSG00000097007 ABL1 ENSG00000172936 MYD88 H. sapiens SDL Slorth 0.97498 View