ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000102974 CTCF H. sapiens SDL Slorth 0.977405 View
ENSG00000097007 ABL1 ENSG00000185104 FAF1 H. sapiens SDL Slorth 0.9774 View
ENSG00000097007 ABL1 ENSG00000132781 MUTYH H. sapiens SDL Slorth 0.977392 View
ENSG00000083290 ULK2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977385 View
ENSG00000097007 ABL1 ENSG00000154001 PPP2R5E H. sapiens SDL Slorth 0.977378 View
ENSG00000097007 ABL1 ENSG00000141564 RPTOR H. sapiens SDL Slorth 0.977368 View
ENSG00000097007 ABL1 ENSG00000116128 BCL9 H. sapiens SDL Slorth 0.977366 View
ENSG00000048462 TNFRSF17 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977353 View
ENSG00000097007 ABL1 ENSG00000127152 BCL11B H. sapiens SDL Slorth 0.977325 View
ENSG00000007312 CD79B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977304 View
ENSG00000076984 MAP2K7 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.9773 View
ENSG00000097007 ABL1 ENSG00000101213 PTK6 H. sapiens SDL Slorth 0.977291 View
ENSG00000004848 ARX ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977286 View
ENSG00000007264 MATK ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977285 View
ENSG00000097007 ABL1 ENSG00000147403 RPL10 H. sapiens SDL Slorth 0.977268 View
ENSG00000097007 ABL1 ENSG00000154310 TNIK H. sapiens SDL Slorth 0.977259 View
ENSG00000097007 ABL1 ENSG00000170296 GABARAP H. sapiens SDL Slorth 0.977238 View
ENSG00000072315 TRPC5 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977214 View
ENSG00000097007 ABL1 ENSG00000117625 RCOR3 H. sapiens SDL Slorth 0.977182 View
ENSG00000097007 ABL1 ENSG00000170248 PDCD6IP H. sapiens SDL Slorth 0.977154 View
ENSG00000097007 ABL1 ENSG00000177272 KCNA3 H. sapiens SDL Slorth 0.977146 View
ENSG00000097007 ABL1 ENSG00000131459 GFPT2 H. sapiens SDL Slorth 0.977134 View
ENSG00000090020 SLC9A1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977131 View
ENSG00000097007 ABL1 ENSG00000100852 ARHGAP5 H. sapiens SDL Slorth 0.97708 View
ENSG00000097007 ABL1 ENSG00000143033 MTF2 H. sapiens SDL Slorth 0.977064 View
ENSG00000068971 PPP2R5B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977059 View
ENSG00000097007 ABL1 ENSG00000185615 PDIA2 H. sapiens SDL Slorth 0.977033 View
ENSG00000028277 POU2F2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.977028 View
ENSG00000097007 ABL1 ENSG00000132694 ARHGEF11 H. sapiens SDL Slorth 0.977023 View
ENSG00000089094 KDM2B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.976989 View
ENSG00000097007 ABL1 ENSG00000163840 DTX3L H. sapiens SDL Slorth 0.976964 View
ENSG00000087274 ADD1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.976963 View
ENSG00000097007 ABL1 ENSG00000107485 GATA3 H. sapiens SDL Slorth 0.976933 View
ENSG00000065029 ZNF76 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.976924 View
ENSG00000097007 ABL1 ENSG00000169554 ZEB2 H. sapiens SDL Slorth 0.976891 View
ENSG00000097007 ABL1 ENSG00000112640 PPP2R5D H. sapiens SDL Slorth 0.976845 View
ENSG00000095787 WAC ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.976771 View
ENSG00000097007 ABL1 ENSG00000172115 CYCS H. sapiens SDL Slorth 0.976733 View
ENSG00000097007 ABL1 ENSG00000164109 MAD2L1 H. sapiens SDL Slorth 0.97667 View
ENSG00000097007 ABL1 ENSG00000131504 DIAPH1 H. sapiens SDL Slorth 0.97661 View