MAP2K7 - ABL1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MAP2K7	ENSG00000076984	No diseases in record	No drugs in record	magnesium ion binding signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein tyrosine kinase activity protein binding ATP binding enzyme binding protein kinase binding protein phosphatase binding	PBS2 (S. cerevisiae) jkk-1 (C. elegans) sek-4 (C. elegans) hep (D. melanogaster)
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)