ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000137710 RDX H. sapiens SDL Slorth 0.974393 View
ENSG00000097007 ABL1 ENSG00000133639 BTG1 H. sapiens SDL Slorth 0.974381 View
ENSG00000097007 ABL1 ENSG00000175634 RPS6KB2 H. sapiens SDL Slorth 0.974369 View
ENSG00000097007 ABL1 ENSG00000147274 RBMX H. sapiens SSL Slorth 0.974355 View
ENSG00000010671 BTK ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.974333 View
ENSG00000097007 ABL1 ENSG00000137193 PIM1 H. sapiens SDL Slorth 0.974327 View
ENSG00000097007 ABL1 ENSG00000136573 BLK H. sapiens SDL Slorth 0.974301 View
ENSG00000097007 ABL1 ENSG00000130037 KCNA5 H. sapiens SDL Slorth 0.974297 View
ENSG00000097007 ABL1 ENSG00000126583 PRKCG H. sapiens SDL Slorth 0.974274 View
ENSG00000097007 ABL1 ENSG00000161638 ITGA5 H. sapiens SDL Slorth 0.974272 View
ENSG00000011454 RABGAP1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.974271 View
ENSG00000097007 ABL1 ENSG00000122882 ECD H. sapiens SDL Slorth 0.974268 View
ENSG00000097007 ABL1 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.97426 View
ENSG00000097007 ABL1 ENSG00000184900 SUMO3 H. sapiens SDL Slorth 0.974252 View
ENSG00000097007 ABL1 ENSG00000167513 CDT1 H. sapiens SSL Slorth 0.974228 View
ENSG00000097007 ABL1 ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.974212 View
ENSG00000097007 ABL1 ENSG00000157540 DYRK1A H. sapiens SDL Slorth 0.974184 View
ENSG00000097007 ABL1 ENSG00000103126 AXIN1 H. sapiens SSL Slorth 0.974161 View
ENSG00000097007 ABL1 ENSG00000130726 TRIM28 H. sapiens SSL Slorth 0.974154 View
ENSG00000097007 ABL1 ENSG00000169045 HNRNPH1 H. sapiens SSL Slorth 0.974152 View
ENSG00000097007 ABL1 ENSG00000117748 RPA2 H. sapiens SDL Slorth 0.974148 View
ENSG00000097007 ABL1 ENSG00000174672 BRSK2 H. sapiens SDL Slorth 0.974134 View
ENSG00000097007 ABL1 ENSG00000114062 UBE3A H. sapiens SSL Slorth 0.97413 View
ENSG00000097007 ABL1 ENSG00000136717 BIN1 H. sapiens SDL Slorth 0.97413 View
ENSG00000097007 ABL1 ENSG00000187239 FNBP1 H. sapiens SDL Slorth 0.97411 View
ENSG00000007237 GAS7 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.974107 View
ENSG00000015285 WAS ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.974056 View
ENSG00000097007 ABL1 ENSG00000170027 YWHAG H. sapiens SDL Slorth 0.974016 View
ENSG00000065613 SLK ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.973956 View
ENSG00000097007 ABL1 ENSG00000175220 ARHGAP1 H. sapiens SDL Slorth 0.973943 View
ENSG00000097007 ABL1 ENSG00000163132 MSX1 H. sapiens SDL Slorth 0.973943 View
ENSG00000097007 ABL1 ENSG00000100888 CHD8 H. sapiens SDL Slorth 0.973938 View
ENSG00000097007 ABL1 ENSG00000105173 CCNE1 H. sapiens SDL Slorth 0.973911 View
ENSG00000097007 ABL1 ENSG00000104884 ERCC2 H. sapiens SDL Slorth 0.973898 View
ENSG00000097007 ABL1 ENSG00000115267 IFIH1 H. sapiens SDL Slorth 0.973885 View
ENSG00000097007 ABL1 ENSG00000142945 KIF2C H. sapiens SDL Slorth 0.973885 View
ENSG00000073712 FERMT2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.973856 View
ENSG00000097007 ABL1 ENSG00000113360 DROSHA H. sapiens SDL Slorth 0.973845 View
ENSG00000097007 ABL1 ENSG00000151247 EIF4E H. sapiens SDL Slorth 0.973831 View
ENSG00000097007 ABL1 ENSG00000105401 CDC37 H. sapiens SSL Slorth 0.97378 View