ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000135090 TAOK3 H. sapiens SDL Slorth 0.971608 View
ENSG00000097007 ABL1 ENSG00000165806 CASP7 H. sapiens SSL Slorth 0.971601 View
ENSG00000097007 ABL1 ENSG00000107758 PPP3CB H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000135924 DNAJB2 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000168806 LCMT2 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000188042 ARL4C H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000163017 ACTG2 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000170385 SLC30A1 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000133704 IPO8 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000148834 GSTO1 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000137285 TUBB2B H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000188641 DPYD H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000138138 ATAD1 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000131238 PPT1 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000182054 IDH2 H. sapiens SDL Slorth 0.9716 View
ENSG00000097007 ABL1 ENSG00000106546 AHR H. sapiens SDL Slorth 0.971598 View
ENSG00000008196 TFAP2B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.97159 View
ENSG00000097007 ABL1 ENSG00000115738 ID2 H. sapiens SDL Slorth 0.97159 View
ENSG00000097007 ABL1 ENSG00000113595 TRIM23 H. sapiens SDL Slorth 0.971566 View
ENSG00000097007 ABL1 ENSG00000103479 RBL2 H. sapiens SSL Slorth 0.97153 View
ENSG00000097007 ABL1 ENSG00000111424 VDR H. sapiens SSL Slorth 0.971519 View
ENSG00000097007 ABL1 ENSG00000135829 DHX9 H. sapiens SSL Slorth 0.971505 View
ENSG00000097007 ABL1 ENSG00000137486 ARRB1 H. sapiens SDL Slorth 0.971471 View
ENSG00000097007 ABL1 ENSG00000186153 WWOX H. sapiens SDL Slorth 0.971437 View
ENSG00000097007 ABL1 ENSG00000128191 DGCR8 H. sapiens SDL Slorth 0.97143 View
ENSG00000097007 ABL1 ENSG00000122779 TRIM24 H. sapiens SSL Slorth 0.971429 View
ENSG00000097007 ABL1 ENSG00000125971 DYNLRB1 H. sapiens SDL Slorth 0.971406 View
ENSG00000097007 ABL1 ENSG00000225830 ERCC6 H. sapiens SDL Slorth 0.971392 View
ENSG00000097007 ABL1 ENSG00000116044 NFE2L2 H. sapiens SSL Slorth 0.971346 View
ENSG00000097007 ABL1 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.971341 View
ENSG00000007866 TEAD3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.97133 View
ENSG00000097007 ABL1 ENSG00000165416 SUGT1 H. sapiens SDL Slorth 0.971307 View
ENSG00000097007 ABL1 ENSG00000124813 RUNX2 H. sapiens SSL Slorth 0.971277 View
ENSG00000097007 ABL1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.97125 View
ENSG00000097007 ABL1 ENSG00000167986 DDB1 H. sapiens SSL Slorth 0.971236 View
ENSG00000097007 ABL1 ENSG00000126453 BCL2L12 H. sapiens SDL Slorth 0.971222 View
ENSG00000097007 ABL1 ENSG00000125618 PAX8 H. sapiens SDL Slorth 0.971215 View
ENSG00000097007 ABL1 ENSG00000145349 CAMK2D H. sapiens SDL Slorth 0.971199 View
ENSG00000097007 ABL1 ENSG00000106462 EZH2 H. sapiens SDL Slorth 0.971187 View
ENSG00000075340 ADD2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.971178 View