ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000175793 SFN H. sapiens SSL Slorth 0.969702 View
ENSG00000097007 ABL1 ENSG00000172175 MALT1 H. sapiens SDL Slorth 0.9697 View
ENSG00000097007 ABL1 ENSG00000115677 HDLBP H. sapiens SSL Slorth 0.969687 View
ENSG00000087263 OGFOD1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.969667 View
ENSG00000097007 ABL1 ENSG00000101251 SEL1L2 H. sapiens SDL Slorth 0.969667 View
ENSG00000097007 ABL1 ENSG00000169710 FASN H. sapiens SDL Slorth 0.969655 View
ENSG00000097007 ABL1 ENSG00000116641 DOCK7 H. sapiens SDL Slorth 0.969651 View
ENSG00000097007 ABL1 ENSG00000168283 BMI1 H. sapiens SSL Slorth 0.969637 View
ENSG00000097007 ABL1 ENSG00000100650 SRSF5 H. sapiens SSL Slorth 0.969634 View
ENSG00000097007 ABL1 ENSG00000150459 SAP18 H. sapiens SSL Slorth 0.969596 View
ENSG00000097007 ABL1 ENSG00000106628 POLD2 H. sapiens SDL Slorth 0.969574 View
ENSG00000097007 ABL1 ENSG00000108094 CUL2 H. sapiens SSL Slorth 0.969552 View
ENSG00000097007 ABL1 ENSG00000157227 MMP14 H. sapiens SDL Slorth 0.969547 View
ENSG00000097007 ABL1 ENSG00000134954 ETS1 H. sapiens SSL Slorth 0.969545 View
ENSG00000097007 ABL1 ENSG00000134323 MYCN H. sapiens SDL Slorth 0.969519 View
ENSG00000097007 ABL1 ENSG00000171960 PPIH H. sapiens SSL Slorth 0.969517 View
ENSG00000097007 ABL1 ENSG00000100401 RANGAP1 H. sapiens SSL Slorth 0.9695 View
ENSG00000097007 ABL1 ENSG00000117676 RPS6KA1 H. sapiens SSL Slorth 0.969494 View
ENSG00000097007 ABL1 ENSG00000157087 ATP2B2 H. sapiens SDL Slorth 0.969492 View
ENSG00000097007 ABL1 ENSG00000113161 HMGCR H. sapiens SDL Slorth 0.969452 View
ENSG00000094631 HDAC6 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.969439 View
ENSG00000097007 ABL1 ENSG00000102054 RBBP7 H. sapiens SSL Slorth 0.969425 View
ENSG00000097007 ABL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.969423 View
ENSG00000097007 ABL1 ENSG00000163932 PRKCD H. sapiens SSL Slorth 0.969407 View
ENSG00000097007 ABL1 ENSG00000146535 GNA12 H. sapiens SDL Slorth 0.969378 View
ENSG00000029639 TFB1M ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.969368 View
ENSG00000063245 EPN1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.969367 View
ENSG00000097007 ABL1 ENSG00000103966 EHD4 H. sapiens SDL Slorth 0.96931 View
ENSG00000097007 ABL1 ENSG00000138668 HNRNPD H. sapiens SDL Slorth 0.969308 View
ENSG00000097007 ABL1 ENSG00000163482 STK36 H. sapiens SDL Slorth 0.969307 View
ENSG00000097007 ABL1 ENSG00000170759 KIF5B H. sapiens SDL Slorth 0.969241 View
ENSG00000037757 MRI1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.969238 View
ENSG00000070770 CSNK2A2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.969233 View
ENSG00000066044 ELAVL1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.969216 View
ENSG00000097007 ABL1 ENSG00000131400 NAPSA H. sapiens SDL Slorth 0.969203 View
ENSG00000097007 ABL1 ENSG00000197879 MYO1C H. sapiens SDL Slorth 0.969123 View
ENSG00000097007 ABL1 ENSG00000196218 RYR1 H. sapiens SDL Slorth 0.969107 View
ENSG00000097007 ABL1 ENSG00000127511 SIN3B H. sapiens SSL Slorth 0.969103 View
ENSG00000097007 ABL1 ENSG00000166508 MCM7 H. sapiens SSL Slorth 0.969088 View
ENSG00000097007 ABL1 ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.969083 View