ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000179583 CIITA H. sapiens SDL Slorth 0.971171 View
ENSG00000097007 ABL1 ENSG00000153487 ING1 H. sapiens SSL Slorth 0.97117 View
ENSG00000097007 ABL1 ENSG00000108984 MAP2K6 H. sapiens SDL Slorth 0.971153 View
ENSG00000097007 ABL1 ENSG00000141736 ERBB2 H. sapiens SSL Slorth 0.971152 View
ENSG00000097007 ABL1 ENSG00000148341 SH3GLB2 H. sapiens SDL Slorth 0.971137 View
ENSG00000097007 ABL1 ENSG00000178209 PLEC H. sapiens SDL Slorth 0.971134 View
ENSG00000097007 ABL1 ENSG00000116141 MARK1 H. sapiens SDL Slorth 0.971105 View
ENSG00000097007 ABL1 ENSG00000100297 MCM5 H. sapiens SSL Slorth 0.971099 View
ENSG00000097007 ABL1 ENSG00000144381 HSPD1 H. sapiens SDL Slorth 0.971096 View
ENSG00000097007 ABL1 ENSG00000114302 PRKAR2A H. sapiens SDL Slorth 0.97109 View
ENSG00000097007 ABL1 ENSG00000108861 DUSP3 H. sapiens SDL Slorth 0.971074 View
ENSG00000097007 ABL1 ENSG00000182578 CSF1R H. sapiens SDL Slorth 0.97107 View
ENSG00000097007 ABL1 ENSG00000101945 SUV39H1 H. sapiens SSL Slorth 0.971042 View
ENSG00000097007 ABL1 ENSG00000157601 MX1 H. sapiens SDL Slorth 0.971009 View
ENSG00000097007 ABL1 ENSG00000166477 LEO1 H. sapiens SDL Slorth 0.971007 View
ENSG00000089250 NOS1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.970998 View
ENSG00000097007 ABL1 ENSG00000100320 RBFOX2 H. sapiens SDL Slorth 0.970994 View
ENSG00000097007 ABL1 ENSG00000105173 CCNE1 H. sapiens SSL Slorth 0.970955 View
ENSG00000079819 EPB41L2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.97092 View
ENSG00000097007 ABL1 ENSG00000127527 EPS15L1 H. sapiens SDL Slorth 0.970909 View
ENSG00000097007 ABL1 ENSG00000116017 ARID3A H. sapiens SDL Slorth 0.97088 View
ENSG00000097007 ABL1 ENSG00000105325 FZR1 H. sapiens SDL Slorth 0.97085 View
ENSG00000097007 ABL1 ENSG00000141968 VAV1 H. sapiens SDL Slorth 0.970827 View
ENSG00000097007 ABL1 ENSG00000143776 CDC42BPA H. sapiens SDL Slorth 0.970824 View
ENSG00000097007 ABL1 ENSG00000108883 EFTUD2 H. sapiens SSL Slorth 0.970804 View
ENSG00000097007 ABL1 ENSG00000103657 HERC1 H. sapiens SDL Slorth 0.970787 View
ENSG00000097007 ABL1 ENSG00000120733 KDM3B H. sapiens SDL Slorth 0.970787 View
ENSG00000097007 ABL1 ENSG00000139734 DIAPH3 H. sapiens SDL Slorth 0.970787 View
ENSG00000097007 ABL1 ENSG00000198677 TTC37 H. sapiens SDL Slorth 0.970706 View
ENSG00000097007 ABL1 ENSG00000169045 HNRNPH1 H. sapiens SDL Slorth 0.970682 View
ENSG00000097007 ABL1 ENSG00000163743 RCHY1 H. sapiens SSL Slorth 0.970673 View
ENSG00000097007 ABL1 ENSG00000106144 CASP2 H. sapiens SDL Slorth 0.970636 View
ENSG00000097007 ABL1 ENSG00000138376 BARD1 H. sapiens SSL Slorth 0.970577 View
ENSG00000087095 NLK ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.970561 View
ENSG00000038382 TRIO ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.970553 View
ENSG00000097007 ABL1 ENSG00000144118 RALB H. sapiens SDL Slorth 0.970519 View
ENSG00000097007 ABL1 ENSG00000101665 SMAD7 H. sapiens SSL Slorth 0.97051 View
ENSG00000097007 ABL1 ENSG00000183072 NKX2-5 H. sapiens SDL Slorth 0.970477 View
ENSG00000097007 ABL1 ENSG00000169139 UBE2V2 H. sapiens SDL Slorth 0.97041 View
ENSG00000097007 ABL1 ENSG00000172534 HCFC1 H. sapiens SDL Slorth 0.970408 View