ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000198898 CAPZA2 H. sapiens SDL Slorth 0.972403 View
ENSG00000097007 ABL1 ENSG00000105325 FZR1 H. sapiens SSL Slorth 0.9724 View
ENSG00000097007 ABL1 ENSG00000138778 CENPE H. sapiens SDL Slorth 0.972399 View
ENSG00000097007 ABL1 ENSG00000145386 CCNA2 H. sapiens SDL Slorth 0.97238 View
ENSG00000097007 ABL1 ENSG00000157106 SMG1 H. sapiens SSL Slorth 0.972377 View
ENSG00000097007 ABL1 ENSG00000125107 CNOT1 H. sapiens SDL Slorth 0.972363 View
ENSG00000097007 ABL1 ENSG00000186432 KPNA4 H. sapiens SDL Slorth 0.97235 View
ENSG00000097007 ABL1 ENSG00000114738 MAPKAPK3 H. sapiens SDL Slorth 0.972311 View
ENSG00000097007 ABL1 ENSG00000197930 ERO1A H. sapiens SDL Slorth 0.972303 View
ENSG00000049245 VAMP3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.972289 View
ENSG00000097007 ABL1 ENSG00000127511 SIN3B H. sapiens SDL Slorth 0.972269 View
ENSG00000097007 ABL1 ENSG00000135945 REV1 H. sapiens SDL Slorth 0.972242 View
ENSG00000085382 HACE1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.97221 View
ENSG00000097007 ABL1 ENSG00000117751 PPP1R8 H. sapiens SDL Slorth 0.972166 View
ENSG00000097007 ABL1 ENSG00000124788 ATXN1 H. sapiens SDL Slorth 0.972161 View
ENSG00000097007 ABL1 ENSG00000159210 SNF8 H. sapiens SDL Slorth 0.972129 View
ENSG00000097007 ABL1 ENSG00000157933 SKI H. sapiens SSL Slorth 0.972094 View
ENSG00000097007 ABL1 ENSG00000268173 AC007192.4 H. sapiens SDL Slorth 0.972087 View
ENSG00000097007 ABL1 ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.972051 View
ENSG00000097007 ABL1 ENSG00000119048 UBE2B H. sapiens SSL Slorth 0.97197 View
ENSG00000097007 ABL1 ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.971929 View
ENSG00000097007 ABL1 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.971903 View
ENSG00000097007 ABL1 ENSG00000142192 APP H. sapiens SDL Slorth 0.9719 View
ENSG00000097007 ABL1 ENSG00000213639 PPP1CB H. sapiens SDL Slorth 0.971823 View
ENSG00000097007 ABL1 ENSG00000110880 CORO1C H. sapiens SDL Slorth 0.97182 View
ENSG00000097007 ABL1 ENSG00000213585 VDAC1 H. sapiens SDL Slorth 0.971776 View
ENSG00000097007 ABL1 ENSG00000107295 SH3GL2 H. sapiens SDL Slorth 0.97172 View
ENSG00000097007 ABL1 ENSG00000137486 ARRB1 H. sapiens SSL Slorth 0.971712 View
ENSG00000097007 ABL1 ENSG00000141985 SH3GL1 H. sapiens SDL Slorth 0.971701 View
ENSG00000097007 ABL1 ENSG00000164070 HSPA4L H. sapiens SDL Slorth 0.971692 View
ENSG00000097007 ABL1 ENSG00000136877 FPGS H. sapiens SDL Slorth 0.971692 View
ENSG00000097007 ABL1 ENSG00000198492 YTHDF2 H. sapiens SDL Slorth 0.971692 View
ENSG00000097007 ABL1 ENSG00000160200 CBS H. sapiens SDL Slorth 0.971692 View
ENSG00000097007 ABL1 ENSG00000162616 DNAJB4 H. sapiens SDL Slorth 0.971692 View
ENSG00000097007 ABL1 ENSG00000149187 CELF1 H. sapiens SDL Slorth 0.971692 View
ENSG00000097007 ABL1 ENSG00000157954 WIPI2 H. sapiens SDL Slorth 0.971692 View
ENSG00000097007 ABL1 ENSG00000123131 PRDX4 H. sapiens SDL Slorth 0.971692 View
ENSG00000097007 ABL1 ENSG00000169750 RAC3 H. sapiens SDL Slorth 0.971681 View
ENSG00000097007 ABL1 ENSG00000138095 LRPPRC H. sapiens SDL Slorth 0.971633 View
ENSG00000097007 ABL1 ENSG00000101349 PAK5 H. sapiens SDL Slorth 0.971631 View