ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000153234 NR4A2 H. sapiens SDL Slorth 0.979853 View
ENSG00000097007 ABL1 ENSG00000116833 NR5A2 H. sapiens SDL Slorth 0.979853 View
ENSG00000097007 ABL1 ENSG00000100281 HMGXB4 H. sapiens SDL Slorth 0.979841 View
ENSG00000097007 ABL1 ENSG00000173334 TRIB1 H. sapiens SDL Slorth 0.97981 View
ENSG00000097007 ABL1 ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.979808 View
ENSG00000097007 ABL1 ENSG00000103510 KAT8 H. sapiens SDL Slorth 0.979782 View
ENSG00000016082 ISL1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979776 View
ENSG00000097007 ABL1 ENSG00000198959 TGM2 H. sapiens SDL Slorth 0.979765 View
ENSG00000097007 ABL1 ENSG00000100485 SOS2 H. sapiens SDL Slorth 0.9797 View
ENSG00000097007 ABL1 ENSG00000120539 MASTL H. sapiens SDL Slorth 0.97968 View
ENSG00000097007 ABL1 ENSG00000160007 ARHGAP35 H. sapiens SDL Slorth 0.979675 View
ENSG00000097007 ABL1 ENSG00000113263 ITK H. sapiens SDL Slorth 0.979634 View
ENSG00000081377 CDC14B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979634 View
ENSG00000049768 FOXP3 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979598 View
ENSG00000097007 ABL1 ENSG00000107263 RAPGEF1 H. sapiens SDL Slorth 0.979583 View
ENSG00000072163 LIMS2 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979567 View
ENSG00000097007 ABL1 ENSG00000137764 MAP2K5 H. sapiens SDL Slorth 0.97955 View
ENSG00000097007 ABL1 ENSG00000138794 CASP6 H. sapiens SDL Slorth 0.97951 View
ENSG00000097007 ABL1 ENSG00000107105 ELAVL2 H. sapiens SDL Slorth 0.979487 View
ENSG00000097007 ABL1 ENSG00000126368 NR1D1 H. sapiens SDL Slorth 0.979485 View
ENSG00000097007 ABL1 ENSG00000100934 SEC23A H. sapiens SDL Slorth 0.979435 View
ENSG00000097007 ABL1 ENSG00000214517 PPME1 H. sapiens SDL Slorth 0.979414 View
ENSG00000097007 ABL1 ENSG00000173933 RBM4 H. sapiens SDL Slorth 0.979406 View
ENSG00000097007 ABL1 ENSG00000205302 SNX2 H. sapiens SDL Slorth 0.979377 View
ENSG00000063660 GPC1 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979353 View
ENSG00000041982 TNC ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979353 View
ENSG00000097007 ABL1 ENSG00000100092 SH3BP1 H. sapiens SDL Slorth 0.979318 View
ENSG00000097007 ABL1 ENSG00000169100 SLC25A6 H. sapiens SDL Slorth 0.979306 View
ENSG00000097007 ABL1 ENSG00000104825 NFKBIB H. sapiens SDL Slorth 0.979267 View
ENSG00000097007 ABL1 ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.979261 View
ENSG00000097007 ABL1 ENSG00000185950 IRS2 H. sapiens SDL Slorth 0.97923 View
ENSG00000097007 ABL1 ENSG00000172071 EIF2AK3 H. sapiens SDL Slorth 0.979219 View
ENSG00000097007 ABL1 ENSG00000099622 CIRBP H. sapiens SDL Slorth 0.979215 View
ENSG00000097007 ABL1 ENSG00000104964 AES H. sapiens SDL Slorth 0.979208 View
ENSG00000097007 ABL1 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.979204 View
ENSG00000097007 ABL1 ENSG00000163947 ARHGEF3 H. sapiens SDL Slorth 0.979176 View
ENSG00000092841 MYL6 ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.979168 View
ENSG00000097007 ABL1 ENSG00000101752 MIB1 H. sapiens SDL Slorth 0.979148 View
ENSG00000097007 ABL1 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.979121 View
ENSG00000097007 ABL1 ENSG00000148660 CAMK2G H. sapiens SDL Slorth 0.979107 View