ABL1

ENSG00000097007 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003785 actin monomer binding
GO:0004515 nicotinate-nucleotide adenylyltransferase activity
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0017124 SH3 domain binding
GO:0019905 syntaxin binding
GO:0030145 manganese ion binding
GO:0051015 actin filament binding
GO:0051019 mitogen-activated protein kinase binding
GO:0070064 proline-rich region binding
GO:0005102 receptor binding

Drugs

Drug name Description
BOSUTINIB Tyrosine-protein kinase ABL inhibitor
DASATINIB Tyrosine-protein kinase ABL inhibitor
IMATINIB Tyrosine-protein kinase ABL inhibitor
NILOTINIB Tyrosine-protein kinase ABL inhibitor
PONATINIB Tyrosine-protein kinase ABL inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor

Diseases

Disease Name
CML
ALL
T-ALL

Orthologs

Gene Organism
abl-1 C. elegans
Abl D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000097007 ABL1 ENSG00000147316 MCPH1 H. sapiens SDL Slorth 0.981636 View
ENSG00000097007 ABL1 ENSG00000145703 IQGAP2 H. sapiens SDL Slorth 0.981635 View
ENSG00000097007 ABL1 ENSG00000169047 IRS1 H. sapiens SDL Slorth 0.981556 View
ENSG00000097007 ABL1 ENSG00000129152 MYOD1 H. sapiens SDL Slorth 0.98155 View
ENSG00000097007 ABL1 ENSG00000132254 ARFIP2 H. sapiens SDL Slorth 0.981458 View
ENSG00000097007 ABL1 ENSG00000154832 CXXC1 H. sapiens SDL Slorth 0.981457 View
ENSG00000097007 ABL1 ENSG00000144848 ATG3 H. sapiens SDL Slorth 0.981448 View
ENSG00000077935 SMC1B ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.981401 View
ENSG00000097007 ABL1 ENSG00000173542 MOB1B H. sapiens SDL Slorth 0.981377 View
ENSG00000097007 ABL1 ENSG00000147614 ATP6V0D2 H. sapiens SDL Slorth 0.981338 View
ENSG00000097007 ABL1 ENSG00000126561 STAT5A H. sapiens SDL Slorth 0.98132 View
ENSG00000097007 ABL1 ENSG00000175832 ETV4 H. sapiens SDL Slorth 0.981282 View
ENSG00000097007 ABL1 ENSG00000182208 MOB2 H. sapiens SDL Slorth 0.981277 View
ENSG00000097007 ABL1 ENSG00000183763 TRAIP H. sapiens SDL Slorth 0.981261 View
ENSG00000097007 ABL1 ENSG00000117020 AKT3 H. sapiens SDL Slorth 0.981214 View
ENSG00000097007 ABL1 ENSG00000136021 SCYL2 H. sapiens SDL Slorth 0.981196 View
ENSG00000097007 ABL1 ENSG00000136827 TOR1A H. sapiens SDL Slorth 0.98119 View
ENSG00000097007 ABL1 ENSG00000108559 NUP88 H. sapiens SDL Slorth 0.981159 View
ENSG00000097007 ABL1 ENSG00000154928 EPHB1 H. sapiens SDL Slorth 0.981117 View
ENSG00000077092 RARB ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.981061 View
ENSG00000097007 ABL1 ENSG00000165671 NSD1 H. sapiens SDL Slorth 0.981056 View
ENSG00000097007 ABL1 ENSG00000121152 NCAPH H. sapiens SDL Slorth 0.981046 View
ENSG00000097007 ABL1 ENSG00000099875 MKNK2 H. sapiens SDL Slorth 0.981044 View
ENSG00000097007 ABL1 ENSG00000198033 TUBA3C H. sapiens SDL Slorth 0.981006 View
ENSG00000097007 ABL1 ENSG00000168209 DDIT4 H. sapiens SDL Slorth 0.980973 View
ENSG00000097007 ABL1 ENSG00000175093 SPSB4 H. sapiens SDL Slorth 0.98095 View
ENSG00000097007 ABL1 ENSG00000171621 SPSB1 H. sapiens SDL Slorth 0.98095 View
ENSG00000097007 ABL1 ENSG00000104881 PPP1R13L H. sapiens SDL Slorth 0.980896 View
ENSG00000097007 ABL1 ENSG00000102010 BMX H. sapiens SDL Slorth 0.980882 View
ENSG00000097007 ABL1 ENSG00000143970 ASXL2 H. sapiens SDL Slorth 0.980868 View
ENSG00000097007 ABL1 ENSG00000167461 RAB8A H. sapiens SDL Slorth 0.980858 View
ENSG00000077279 DCX ENSG00000097007 ABL1 H. sapiens SDL Slorth 0.980839 View
ENSG00000097007 ABL1 ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.980832 View
ENSG00000097007 ABL1 ENSG00000152284 TCF7L1 H. sapiens SDL Slorth 0.980832 View
ENSG00000097007 ABL1 ENSG00000189079 ARID2 H. sapiens SDL Slorth 0.98083 View
ENSG00000097007 ABL1 ENSG00000112335 SNX3 H. sapiens SDL Slorth 0.980829 View
ENSG00000097007 ABL1 ENSG00000214717 ZBED1 H. sapiens SDL Slorth 0.980825 View
ENSG00000097007 ABL1 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.980822 View
ENSG00000097007 ABL1 ENSG00000146872 TLK2 H. sapiens SDL Slorth 0.980817 View
ENSG00000097007 ABL1 ENSG00000121067 SPOP H. sapiens SDL Slorth 0.980815 View